SCHEMBL131533

SCHEMBL131533

COc1ccc(C=NN(Cc2ccccc2)c2ccccc2)c2ccccc12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.60
MEN1 O00255 8/20 0.60
KMT2A Q03164 8/20 0.60
LMNA P02545 4/20 0.60
MAPK1 P28482 3/20 0.60
ATM Q13315 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
ALDH1A1 P00352 7/20 0.55
GAA P10253 3/20 0.55
POLB P06746 3/20 0.55
KDM4E B2RXH2 2/20 0.55
SMN1; SMN2 Q16637 3/20 0.50
MCL1 Q07820 1/20 0.50
PKM P14618 1/20 0.48
HSP90AA1 P07900 1/20 0.48
TDP1 Q9NUW8 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
GCGR P47871 2/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL170236 0.81 MAPT (0.59) MAPTMEN1KMT2ALMNAMAPK1
SCHEMBL11287677 0.81 MEN1 (0.51) MAPTMEN1KMT2ALMNAMAPK1
SCHEMBL11287115 0.80 MEN1 (0.58) MAPTMEN1KMT2ALMNAMAPK1
SCHEMBL1702914 0.80 MAPT (0.65) MAPTMEN1KMT2ALMNAALDH1A1
SCHEMBL10338601 0.78 MAPT (0.56) MAPTMEN1KMT2ALMNAMAPK1
SCHEMBL10338602 0.78 MAPT (0.56) MAPTMEN1KMT2ALMNAMAPK1
SCHEMBL8498157 0.73 G6PC1 (0.72) MAPTMEN1KMT2ALMNAMAPK1
SCHEMBL8498156 0.73 G6PC1 (0.72) MAPTMEN1KMT2ALMNAMAPK1
SCHEMBL9809671 0.71 MAPT (0.79) MAPTMEN1KMT2ALMNAMAPK1
SCHEMBL9809673 0.71 MAPT (0.79) MAPTMEN1KMT2ALMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 105 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103242167-B Amine compound, photoelectric conductor for electronic photography, image forming method, image forming apparatus and handle box RICOH CO., LTD. (JP) 2016-02-24 CN disclosed
US-9235146-B2 Photoconductor RICOH COMPANY, LTD. (JP) 2016-01-12 US disclosed
US-9040215-B2 Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2015-05-26 US disclosed
US-9005856-B2 Hydroxygallium porphyrazine derivative mixture and electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2015-04-14 US disclosed
US-20150079509-A1 PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2015-03-19 US disclosed
US-8889324-B2 Image bearing member, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2014-11-18 US disclosed
US-8809543-B2 Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, and process cartridge for electrophotographic image forming apparatus RICOH COMPANY, LTD. (JP) 2014-08-19 US disclosed
US-8586270-B2 Electrophotographic photoconductor, electrophotographic method, and electrophotographic apparatus RICOH COMPANY, LTD. (JP) 2013-11-19 US disclosed
CN-103242167-A Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH CO LTD 2013-08-14 CN disclosed
US-20130202994-A1 AMINE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-08-08 US disclosed
US-4808503-A SENSITIVITY, DURABILITY MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1989-02-28 US disclosed
EP-0270685-A1 PHOTOSENSITIVE MATERIAL FOR ELECTROPHOTOGRAPHY MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-06-15 EP disclosed
US-4716220-A CHARGE CARRIER GENERATING MATERIALS RICOH CO., LTD. (JP) 1987-12-29 US disclosed
US-4708921-A Photosensitive material containing disazo compound for use in electrophotography RICOH CO., LTD. (JP) 1987-11-24 US disclosed
US-4702979-A ELECTROCONDUCTIVE CATHODE LAYER, PHOTOCONDUCTIVE LAYER OF CHARGE-GENERATING ORGANIC PIGMENT, ANODIC ION REACTION AT INTERFACE WHEN IRRADIATED RICOH CO., LTD. (JP) 1987-10-27 US disclosed
US-4672149-A PHOTOACTIVE LAYER CONTAINING A DISAZO PIGMENT; SOLAR CELLS; EFFICIENCY RICOH CO., LTD. (JP) 1987-06-09 US disclosed
US-4663442-A ELECTROGRAPHY, PHOTOSENSITIVITY RICOH CO., LTD. (JP) 1987-05-05 US disclosed
US-4619878-A Tetrazonium salt compound, disazo compound, method for preparing the same, and photosensitive material containing said disazo compound for use in electrophotography RICOH CO., LTD. (JP) 1986-10-28 US disclosed
US-4582771-A Disazo compound, method for preparing the same, and electrophotographic element containing the same for use in electrophotography RICOH CO., LTD. (JP) 1986-04-15 US disclosed
US-4540643-A Tetrazonium salt compounds, novel disazo compounds, method for the production thereof and disazo compound-containing electrophotographic elements RICOH CO., LTD. (JP) 1985-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130202994-A1 AMINE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE ARL1, ATXN2L, AHR MAPT 2185/4885MEN1 764/4885KMT2A 2164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.