Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | PYCR1 | P32322 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4528233 | 0.74 | SLC6A2 (0.52) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL17288624 | 0.72 | SLC6A2 (0.40) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL9810146 | 0.72 | SLC6A2 (0.50) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL10348475 | 0.71 | SLC6A2 (0.59) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL3385591 | 0.69 | SLC6A2 (0.56) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL27669066 | 0.68 | SLC6A2 (0.45) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL3120157 | 0.67 | SLC6A2 (0.54) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL19961863 | 0.67 | SMN1; SMN2 (0.48) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL8121696 | 0.66 | SLC6A2 (0.58) | SLC6A2TAAR1LMNACYP2D6TRPA1 | |
| SCHEMBL94458 | 0.66 | SLC6A2 (0.58) | SLC6A2TAAR1LMNACYP2D6TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0060640-A1 | 5,6,7-Trinor-4,8-inter-m-phenylene PGI derivatives and pharmaceutical compositions containing them | TORAY INDUSTRIES, INC. (JP) | 1982-09-22 | — | — | EP | disclosed |