Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8121696 | 0.84 | SLC6A2 (0.58) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL7666090 | 0.84 | SLC6A2 (0.58) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL8586071 | 0.79 | SLC6A2 (0.58) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL1900874 | 0.79 | SLC6A2 (0.58) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL19118092 | 0.78 | SLC6A2 (0.52) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL1572105 | 0.78 | SLC6A2 (0.64) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL347187 | 0.78 | SLC6A2 (0.64) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL1357604 | 0.77 | SLC6A2 (0.50) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL6552350 | 0.77 | SMN1; SMN2 (0.50) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL28358439 | 0.76 | SLC6A2 (0.61) | SLC6A2TAAR1CYP2D6LMNATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 316 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4647912-B2 | — | — | 2011-03-09 | — | — | JP | claimed |
| JP-2005514427-A | — | — | 2005-05-19 | — | — | JP | claimed |
| EP-1469729-A1 | VIRUCIDAL DISINFECTANT | Lonza AG (CH) | 2004-10-27 | — | — | EP | claimed |
| WO-2003059062-A1 | VIRUCIDAL DISINFECTANT | LONZA AG (CH) | 2003-07-24 | — | — | WO | claimed |
| WO-2023176796-A1 | SCAR FORMATION INHIBITOR, FIBROBLAST PROLIFERATION INHIBITOR, AND METHOD FOR PRODUCING NANOPARTICLES | 国立大学法人東北大学 | 2023-09-21 | — | — | WO | disclosed |
| US-20230099694-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2023-03-30 | — | — | US | disclosed |
| US-11273168-B2 | Methods of treating anxiety by administering a substituted quinolone | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-03-15 | — | — | US | disclosed |
| US-20210113556-A1 | Piperazine-Substituted Benzothiophenes For Treatment of Mental Disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-04-22 | — | — | US | disclosed |
| US-20210052575-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-02-25 | — | — | US | disclosed |
| US-20200281951-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING OR PREVENTING DISORDERS CAUSED BY REDUCED NEUROTRANSMISSION OF SEROTONIN, NOREPHNEPHRINE OR DOPAMINE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-09-10 | — | — | US | disclosed |
| US-20200237755-A1 | Piperazine-Substituted Benzothiophenes For Treatment of Mental Disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-07-30 | — | — | US | disclosed |
| US-RE48059-E1 | Piperazine-substituted benzothiophenes for treatment of mental disorders | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2020-06-23 | — | — | US | disclosed |
| US-4238501-A | INSECTICIDES, MITICIDES, PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-09 | — | — | US | disclosed |
| US-4237162-A | MITICIDES, LARVACIDES, INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-12-02 | — | — | US | disclosed |
| US-4189498-A | FUNGICIDES, ARTHROPODICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-02-19 | — | — | US | disclosed |
| US-4185112-A | INSECTICIDES, MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1980-01-22 | — | — | US | disclosed |
| EP-0004624-A2 | Chromanon derivatives, process for their preparation, and their use as medicines and growth-promoting agents | BAYER AG (DE) | 1979-10-17 | — | — | EP | disclosed |
| EP-0001424-A1 | Insecticidal agents | BAYER AG (DE) | 1979-04-18 | — | — | EP | disclosed |
| EP-0001428-A1 | Insecticidal and acaricidal agents containing chroman derivatives, their preparation and their use, as well as chroman derivatives and their preparation | BAYER AG (DE) | 1979-04-18 | — | — | EP | disclosed |
| EP-0000377-A1 | Process for the preparation of chromone derivatives, new chromone derivatives and their use as plant-protecting agents | BAYER AG (DE) | 1979-01-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230099694-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, BRPF3, BRD4 | SLC6A2 108/4885TAAR1 468/4885CYP2D6 107/4885 |
| US-11273168-B2 | Methods of treating anxiety by administering a substituted quinolone | CRH, MC2R, HTR3C | SLC6A2 14/4885TAAR1 99/4885CYP2D6 1256/4885 |
| US-20200237755-A1 | Piperazine-Substituted Benzothiophenes For Treatment of Mental Disorders | GRIN2C, TPH1, HTR2C | SLC6A2 94/4885TAAR1 109/4885CYP2D6 351/4885 |
| US-20200281951-A1 | HETEROCYCLIC COMPOUNDS FOR TREATING OR PREVENTING DISORDERS CAUSED BY REDUCED NEUROTRANSMISSION OF SEROTONIN, NOREPHNEPHRINE OR DOPAMINE | MC2R, SLC6A2, CRH | SLC6A2 2/4885TAAR1 66/4885CYP2D6 855/4885 |
| US-20210052575-A1 | PIPERAZINE-SUBSTITUTED BENZOTHIOPHENE DERIVATIVES AS ANTIPSYCHOTIC AGENTS | SUZ12, SULT2A1, CYP4Z1 | SLC6A2 254/4885TAAR1 411/4885CYP2D6 70/4885 |
| US-20210113556-A1 | Piperazine-Substituted Benzothiophenes For Treatment of Mental Disorders | GRIN2C, TPH1, HTR2C | SLC6A2 94/4885TAAR1 109/4885CYP2D6 351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.