Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31166039 | 0.87 | SLC6A2 (0.48) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL1157985 | 0.85 | SLC6A2 (0.56) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL872871 | 0.83 | SLC6A2 (0.54) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL7492795 | 0.81 | SLC6A2 (0.52) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL8025855 | 0.81 | LMNA (0.54) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL7929657 | 0.81 | SLC6A2 (0.52) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL313697 | 0.81 | SLC6A2 (0.52) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL14461582 | 0.79 | SLC6A2 (0.56) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL22029800 | 0.79 | SLC6A2 (0.50) | SLC6A2TAAR1CYP2D6LMNATRPA1 | |
| SCHEMBL28653302 | 0.79 | TAAR1 (0.50) | SLC6A2TAAR1CYP2D6LMNATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114436781-B | Preparation method of substituted phenol compound | 安徽觅拓材料科技有限公司 | 2023-03-24 | — | — | CN | claimed |
| CN-114436781-A | Preparation method of substituted phenol compound | 安徽觅拓材料科技有限公司 | 2022-05-06 | — | — | CN | claimed |
| EP-1979362-B1 | NOVEL SILANE COMPOUNDS AND USE THEREOF IN ORDER TO FUNCTIONALISE SOLID MEDIA AND IMMOBILISE BIOLOGICAL MOLECULES ON SAID MEDIA | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2010-12-15 | — | — | EP | claimed |
| CN-114436781-B | Preparation method of substituted phenol compound | 安徽觅拓材料科技有限公司 | 2023-03-24 | — | — | CN | disclosed |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2022-05-10 | — | — | US | disclosed |
| CN-114436781-A | Preparation method of substituted phenol compound | 安徽觅拓材料科技有限公司 | 2022-05-06 | — | — | CN | disclosed |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2017-11-02 | — | — | US | disclosed |
| US-20120309922-A1 | HYDROXY-TERMINATED SILOXANE, POLYSILOXANE-POLYCARBONATE COPOLYMER, AND PREPARATION METHOD THEREOF | SAMYANG CORPORATION (KR) | 2012-12-06 | — | — | US | disclosed |
| EP-0977743-A1 | PROTEASE INHIBITORS | Smithkline Beecham (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1998049152-A1 | PROTEASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309922-A1 | HYDROXY-TERMINATED SILOXANE, POLYSILOXANE-POLYCARBONATE COPOLYMER, AND PREPARATION METHOD THEREOF | SEM1, P4HA1, SULT1A1 | SLC6A2 4720/4885TAAR1 2600/4885CYP2D6 2060/4885 |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | HDGF, F11, F12 | SLC6A2 4635/4885TAAR1 3874/4885CYP2D6 3820/4885 |
| US-20170312363-A1 | MULTIFUNCTIONALIZED POLYETHYLENE GLYCOL DERIVATIVE AND PREPARATION METHOD THEREFOR | HDGF, F11, F12 | SLC6A2 4635/4885TAAR1 3874/4885CYP2D6 3820/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.