Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.48 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1744767 | 0.84 | GABRA1 (0.58) | GABRA1GABRB2POLBXDHMEN1 | |
| SCHEMBL1244606 | 0.79 | GABRA1 (0.59) | GABRA1GABRB2POLBXDHMEN1 | |
| SCHEMBL1420694 | 0.79 | GABRA1 (0.64) | GABRA1GABRB2POLBXDHMEN1 | |
| SCHEMBL6423969 | 0.79 | GABRA1 (0.41) | GABRA1GABRB2POLBXDHMEN1 | |
| SCHEMBL7737611 | 0.75 | GABRA1 (0.59) | GABRA1GABRB2POLBXDHMEN1 | |
| SCHEMBL9283347 | 0.74 | GABRA1 (0.48) | GABRA1GABRB2POLBXDHMEN1 | |
| SCHEMBL8517508 | 0.73 | GABRA1 (0.47) | GABRA1GABRB2POLBXDHMEN1 | |
| SCHEMBL44699 | 0.72 | GABRA1 (0.48) | GABRA1GABRB2POLBXDHMEN1 | |
| SCHEMBL9296359 | 0.72 | GABRA1 (0.47) | GABRA1GABRB2POLBXDHMEN1 | |
| SCHEMBL3819967 | 0.72 | GABRA1 (0.68) | GABRA1GABRB2POLBXDHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4322529-A | Tertiary-alkylamine salts of azine dyestuffs | CIBA-GEIGY CORPORATION (US) | 1982-03-30 | — | — | US | disclosed |
| US-3994872-A | SOLUBILITY | CIBA-GEIGY CORPORATION (US) | 1976-11-30 | — | — | US | disclosed |