Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9115480 | 0.86 | ALOX5 (0.48) | GABRA1GABRB2KDM4EDHFRGAA | |
| SCHEMBL4149652 | 0.83 | GABRA1 (0.59) | GABRA1GABRB2KDM4EPOLBAKR1B1 | |
| SCHEMBL4045452 | 0.83 | GABRA1 (0.48) | GABRA1GABRB2KDM4EPOLBAKR1B1 | |
| SCHEMBL11766748 | 0.81 | HSPA5 (0.43) | GABRA1GABRB2KDM4EDHFRPOLB | |
| SCHEMBL9960069 | 0.81 | ALDH1A1 (0.47) | GABRA1GABRB2KDM4EPOLBGAA | |
| SCHEMBL2461750 | 0.81 | XDH (0.48) | GABRA1GABRB2KDM4EDHFRPOLB | |
| SCHEMBL7852200 | 0.81 | GABRA1 (0.47) | GABRA1GABRB2KDM4EDHFRPOLB | |
| SCHEMBL1420217 | 0.81 | GABRA1 (0.47) | GABRA1GABRB2KDM4EDHFRPOLB | |
| SCHEMBL10487312 | 0.80 | GABRA1 (0.47) | GABRA1GABRB2KDM4EPOLBAKR1B1 | |
| SCHEMBL9284341 | 0.80 | DHFR (0.43) | GABRA1GABRB2KDM4EDHFRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0141419-B1 | 3,5-DIALKYL-4-HYDROXYPHENYL-SUBSTITUTED DERIVATIVES | The B.F. GOODRICH Company (US) | 1988-03-09 | — | — | EP | claimed |
| EP-0365127-B1 | Substituted triazines | UNIROYAL CHEM CO INC (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5120844-A | Antiozonants for rubber | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1992-06-09 | — | — | US | disclosed |
| US-4972010-A | OXIDATION RESISTANCE FOR TIRES, RUBBERS | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1990-11-20 | — | — | US | disclosed |
| EP-0365127-A1 | Substituted triazines | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1990-04-25 | — | — | EP | disclosed |
| US-4038434-A | ANTIOXIDANT STABILIZED EDIBLE COMPOSITIONS | HOWARD HALL & COMPANY (US) | 1977-07-26 | — | — | US | disclosed |
| US-4013621-A | OXIDATION RESISTANCE | CIBA-GEIGY CORPORATION (US) | 1977-03-22 | — | — | US | disclosed |