SCHEMBL11288337

SCHEMBL11288337

Cc1c(N)cc(Br)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.59
MAPT P10636 6/20 0.59
MEN1 O00255 6/20 0.59
KMT2A Q03164 6/20 0.59
POLB P06746 4/20 0.59
L3MBTL1 Q9Y468 2/20 0.59
HTT P42858 1/20 0.59
FTO Q9C0B1 1/20 0.51
ADORA2A P29274 5/20 0.50
MAOA P21397 3/20 0.50
CSNK1A1 P48729 2/20 0.50
CSNK1D P48730 2/20 0.50
CSNK1G1 Q9HCP0 2/20 0.50
FGR P09769 1/20 0.50
PIM1 P11309 1/20 0.50
DYRK1A Q13627 1/20 0.50
HIPK2 Q9H2X6 1/20 0.50
CYP1A2 P05177 3/20 0.45
CYP1A1 P04798 1/20 0.45
SMN1; SMN2 Q16637 5/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2256190 0.82 ADORA2A (0.53) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL27918992 0.82 MAPT (0.62) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL11318333 0.79 ALDH1A1 (0.42) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL11320356 0.79 ALDH1A1 (0.42) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL726339 0.79 CYP1A1 (0.66) ALDH1A1MAPTMEN1KMT2APOLB
1-Amino-2,4-Dibromoanthra-Quinone SCHEMBL3272427 0.77 FTO (0.64) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL10808664 0.75 MEN1 (0.62) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL21451669 0.75 TTR (0.46) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL4593464 0.74 ALDH1A1 (0.67) ALDH1A1MAPTMEN1KMT2APOLB
SCHEMBL1850298 0.74 MEN1 (1.00) ALDH1A1MAPTMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0044666-A2 Helichromic compounds and displays MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-01-27 EP disclosed
US-4296044-A AMINATION, QUATERNIZATION BAYER AKTIENGESELLSCHAFT (DE) 1981-10-20 US disclosed
US-4216146-A Azo(hydrazo)-anthraquinone compounds CIBA-GEIGY AG (CH) 1980-08-05 US disclosed