Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 5/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.62 |
| ▸ | MAOA | P21397 | 2/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.53 |
| ▸ | CSNK1G1 | Q9HCP0 | 2/20 | 0.53 |
| ▸ | FGR | P09769 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.53 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1-Amino-2,4-Dibromoanthra-Quinone SCHEMBL3272427 | 0.87 | FTO (0.64) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL10808664 | 0.85 | MEN1 (0.62) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL726339 | 0.82 | CYP1A1 (0.66) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL11180975 | 0.82 | FTO (0.59) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL10435103 | 0.82 | FTO (0.59) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL11288337 | 0.82 | ALDH1A1 (0.59) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL3582220 | 0.80 | FTO (0.60) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL11179290 | 0.78 | FTO (0.55) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL8657508 | 0.78 | MAPT (0.72) | MAPTMEN1KMT2AALDH1A1POLB | |
| SCHEMBL3660357 | 0.78 | FTO (0.71) | MAPTMEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103319438-B | 4-position replaces anthra [1,2-c] [1,2,5] thiadiazoles-6,11-derovatives and its preparation method and application | ARMY MEDICAL UNIV. NO.2, CHINESE PLA (CN) | 2016-03-02 | — | — | CN | disclosed |
| CN-103319438-A | 4-substituted anthra[1,2-c][1,2,5]thiadiazole-6,11-dione derivative and its preparation method and application | UNIV PLA 2ND MILITARY MEDICAL | 2013-09-25 | — | — | CN | disclosed |