SCHEMBL1128835

SCHEMBL1128835

O=C1CCN(C(=O)OCC2c3ccccc3-c3ccccc32)CC1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.47
KMT2A Q03164 3/20 0.46
FABP5 Q01469 3/20 0.45
FABP7 O15540 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
TSHR P16473 1/20 0.44
EPHX2 P34913 1/20 0.43
ALDH1A1 P00352 3/20 0.41
F10 P00742 1/20 0.41
NPSR1 Q6W5P4 2/20 0.40
MAPT P10636 1/20 0.40
ALOX15 P16050 1/20 0.40
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29729550 1.00 POLB (0.47) POLBKMT2AFABP5FABP7L3MBTL1
SCHEMBL6922053 0.95 POLB (0.44) POLBKMT2AFABP5FABP7L3MBTL1
SCHEMBL28263416 0.92 TSHR (0.45) POLBKMT2AFABP5FABP7L3MBTL1
SCHEMBL13327274 0.90 POLB (0.52) POLBKMT2AFABP5FABP7L3MBTL1
SCHEMBL22397770 0.90 POLB (0.52) POLBKMT2AFABP5FABP7L3MBTL1
SCHEMBL15636439 0.87 KMT2A (0.45) POLBKMT2AFABP5FABP7L3MBTL1
SCHEMBL30824716 0.87 TSHR (0.50) POLBKMT2AFABP5FABP7L3MBTL1
SCHEMBL30555288 0.87 TSHR (0.50) POLBKMT2AFABP5FABP7L3MBTL1
SCHEMBL8222797 0.87 TSHR (0.50) POLBKMT2AFABP5FABP7L3MBTL1
SCHEMBL31220527 0.85 TSHR (0.52) POLBKMT2AFABP5FABP7L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1934561-B1 IMPROVED TIME/TEMPERATURE INDICATORS SUN CHEMICAL CORP (US) 2018-11-07 EP claimed
US-20080269050-A1 Time/Temperature Indicators SUN CHEMICAL CORPORATION (US) 2008-10-30 US claimed
EP-1934561-A1 IMPROVED TIME/TEMPERATURE INDICATORS Sun Chemical Corporation (US) 2008-06-25 EP claimed
WO-2007035365-A1 IMPROVED TIME/TEMPERATURE INDICATORS SUN CHEMICAL CORPORATION (US) 2007-03-29 WO claimed
WO-2006091465-A1 TIME/TEMPERATURE INDICATORS, THEIR PREPARATION AND USE SUN CHEMICAL CORPORATION (US) 2006-08-31 WO claimed
WO-2006091464-A1 IMPROVED TIME/ TEMPERATURE INDICATORS SUN CHEMICAL CORPORATION (US) 2006-08-31 WO claimed
US-20260144788-A1 COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF UBIX THERAPEUTICS, INC. (KR) 2026-05-28 US disclosed
EP-4606799-A1 COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF Ubix Therapeutics, Inc. (KR) 2025-08-27 EP disclosed
EP-4592275-A2 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE Redwood Bioscience, Inc. (US) 2025-07-30 EP disclosed
EP-3074010-B1 HYDRAZINYL-PYRROLO COMPOUNDS AND METHODS FOR PRODUCING A CONJUGATE REDWOOD BIOSCIENCE INC (US) 2025-05-14 EP disclosed
US-20250121083-A1 Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) Antibody-Maytansine Conjugates and Methods of Use Thereof ARES CAPITAL CORPORATION, AS COLLATERAL AGENT 2025-04-17 US disclosed
US-12215080-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate REDWOOD BIOSCIENCE, INC. (US) 2025-02-04 US disclosed
CN-119264119-A Preparation method and application of FLT3 degradation agent based on pyrazinecarboxamide skeleton 中国科学院上海有机化学研究所 2025-01-07 CN disclosed
WO-2002081435-A1 SULPHONES WHICH MODULATE THE ACTION OF GAMMA SECRETASE MERCK SHARP & DOHME LIMITED (GB) 2002-10-17 WO disclosed
US-6384065-B1 CONTROL THE FUNCTIONS OF PROTEINS SUCH AS ENZYMES AND RECEPTOR FORTREATING INFLAMMATORY DISEASES SUCH AS RHEUMATOID ARTHRITIS, TOYAMA CHEMICAL CO., LTD. (JP) 2002-05-07 US disclosed
US-6344449-B1 HEADACHE AND MORPHINE DEPENDENCE DR. KARL THOMAE GMBH (DE) 2002-02-05 US disclosed
US-20010036946-A1 Modified amino acids, pharmaceuticals containing these compounds and method for their production RUDOLF KLAUS (DE) 2001-11-01 US disclosed
EP-1076056-A1 NOVEL SPIRO COMPOUNDS OR SALTS THEREOF AND PREVENTIVES/REMEDIES FOR AUTOIMMUNE DISEASES AND AP-1 INHIBITORS CONTAINING THE SAME TOYAMA CHEMICAL CO., LTD. (JP) 2001-02-14 EP disclosed
EP-0927192-A1 MODIFIED AMINOACIDS, PHARMACEUTICALS CONTAINING THESE COMPOUNDS AND METHOD FOR THEIR PRODUCTION Dr. Karl Thomae GmbH (DE) 1999-07-07 EP disclosed
WO-1998011128-A1 MODIFIED AMINOACIDS, PHARMACEUTICALS CONTAINING THESE COMPOUNDS AND METHOD FOR THEIR PRODUCTION DR. KARL THOMAE GMBH (DE) 1998-03-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144788-A1 COMPOUND FOR SHP2 PROTEIN DEGRADATION AND MEDICAL USES THEREOF PTPN6, PTPN1, PTPN11 POLB 4113/4885KMT2A 2438/4885FABP5 1538/4885
US-12215080-B2 Hydrazinyl-pyrrolo compounds and methods for producing a conjugate DNPEP, QPCT, PDS5A POLB 3676/4885KMT2A 1630/4885FABP5 2313/4885
US-20250121083-A1 Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) Antibody-Maytansine Conjugates and Methods of Use Thereof TACR3, CASR, CAMK2D POLB 4883/4885KMT2A 3623/4885FABP5 2641/4885
US-20010036946-A1 Modified amino acids, pharmaceuticals containing these compounds and method for their production PTMS, SRMS, OPRM1 POLB 2814/4885KMT2A 2655/4885FABP5 2817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.