Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 6/20 | 0.43 |
| ▸ | HTR2C | P28335 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11292863 | 0.89 | DRD2 (0.51) | TSHRHTR2AHTR2CKCNH2LMNA | |
| SCHEMBL11280131 | 0.87 | DRD2 (0.57) | TSHRHTR2AHTR2CKCNH2LMNA | |
| SCHEMBL11282395 | 0.79 | LMNA (0.54) | ALDH1A1TSHRHTR2AHTR2CKCNH2 | |
| SCHEMBL11285348 | 0.76 | DRD2 (0.45) | TSHRHTR2AHTR2CKCNH2LMNA | |
| SCHEMBL11288334 | 0.76 | DRD2 (0.53) | TSHRHTR2AHTR2CKCNH2LMNA | |
| SCHEMBL11287182 | 0.76 | DRD2 (0.57) | TSHRHTR2AHTR2CKCNH2MEN1 | |
| SCHEMBL11277513 | 0.75 | DRD2 (0.56) | ALDH1A1TSHRHTR2AHTR2CKCNH2 | |
| SCHEMBL11285556 | 0.73 | DRD2 (0.44) | LMNADRD2 | |
| SCHEMBL11283016 | 0.73 | DRD2 (0.53) | ALDH1A1HTTHTR2AHTR2CMAPT | |
| SCHEMBL11282980 | 0.72 | DRD2 (0.41) | TSHRHTR2AHTR2CKCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4353900-A | HYPOTENSIVE, ANTIARRHYTHMIA, CARDIOTONIC, VASODILATORS | SYNTEX (U.S.A.) INC. (US) | 1982-10-12 | — | — | US | disclosed |