Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.36 |
| ▸ | MERTK | Q12866 | 1/20 | 0.36 |
| ▸ | DNM2 | P50570 | 2/20 | 0.35 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CCR4 | P51679 | 2/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3674953 | 0.82 | HRH4 (0.43) | HRH4MERTKDNM2MAPK8ALDH1A1 | |
| SCHEMBL28106506 | 0.78 | PDPK1 (0.40) | HRH4MERTKALDH1A1MKNK1PKM | |
| SCHEMBL8088117 | 0.78 | DNM2 (0.56) | HRH4MERTKDNM2MAPK8 | |
| SCHEMBL18615429 | 0.76 | MKNK1 (0.48) | MERTKALDH1A1CXCR4EIF2AK2MKNK1 | |
| SCHEMBL11090421 | 0.76 | DNM2 (0.58) | HRH4MERTKDNM2MAPK8 | |
| SCHEMBL11262313 | 0.73 | PKM (0.33) | SLC47A1PKM | |
| SCHEMBL18434686 | 0.71 | CLK1 (0.42) | MAPK8CXCR4 | |
| SCHEMBL11086984 | 0.70 | PKM (0.36) | MERTKMAPK8ALDH1A1PKM | |
| SCHEMBL3675383 | 0.68 | — | — | |
| SCHEMBL18608757 | 0.67 | CDC7 (0.52) | MAPK8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0067610-A1 | Penicillins, a process for their preparation and compositions containing them | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | disclosed |