Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM2 | P50570 | 3/20 | 0.56 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.50 |
| ▸ | MERTK | Q12866 | 5/20 | 0.49 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | FLT3 | P36888 | 4/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 4/20 | 0.42 |
| ▸ | GAS6 | Q14393 | 4/20 | 0.42 |
| ▸ | AXL | P30530 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11090421 | 0.98 | DNM2 (0.58) | DNM2HRH4MERTKKCNH3MAPK8 | |
| SCHEMBL3674953 | 0.88 | HRH4 (0.43) | DNM2HRH4MERTKMAPK8TLR8 | |
| SCHEMBL1401613 | 0.81 | DNM2 (0.78) | DNM2HRH4MERTKKCNH3MAPK8 | |
| SCHEMBL28248600 | 0.81 | DNM2 (0.57) | DNM2HRH4MERTKKCNH3MAPK8 | |
| SCHEMBL28106506 | 0.80 | PDPK1 (0.40) | HRH4MERTKKMT2AMAPTHTT | |
| SCHEMBL2574691 | 0.80 | DNM2 (0.59) | DNM2HRH4MERTKKCNH3MAPK8 | |
| SCHEMBL2574817 | 0.80 | DNM2 (0.56) | DNM2HRH4MERTKKCNH3MAPK8 | |
| SCHEMBL18615429 | 0.79 | MKNK1 (0.48) | MERTKKMT2AFLT3TYRO3GAS6 | |
| SCHEMBL17561037 | 0.79 | DNM2 (0.55) | DNM2HRH4MERTKKCNH3MAPK8 | |
| SCHEMBL11288636 | 0.78 | SLC47A1 (0.37) | DNM2HRH4MERTKMAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000264888-A | BICYCLIC PYRIMIDINE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, ITS PRODUCTION, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEM RES CENTER | 2000-09-26 | — | — | JP | disclosed |