SCHEMBL11288937

SCHEMBL11288937

COC(C(=O)c1ccccc1)c1ccc(F)cc1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
CYP3A4 P08684 1/20 0.54
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
NPC1 O15118 2/20 0.49
POLB P06746 1/20 0.49
MAPT P10636 1/20 0.49
RAB9A P51151 1/20 0.49
KDM4E B2RXH2 1/20 0.48
GAA P10253 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.45
LMNA P02545 1/20 0.45
ALPG P10696 1/20 0.45
HPGD P15428 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6201112 0.93 ALDH1A1 (0.54) ALDH1A1CYP3A4MEN1KMT2ANPC1
SCHEMBL6319785 0.91 CES2 (0.43) ALDH1A1CYP3A4MEN1KMT2ANPC1
SCHEMBL26160 0.88 ALDH1A1 (0.68) ALDH1A1CYP3A4MEN1KMT2ANPC1
SCHEMBL10018352 0.88 ALDH1A1 (0.68) ALDH1A1CYP3A4MEN1KMT2ANPC1
Water SCHEMBL23466907 0.86 ALDH1A1 (0.66) ALDH1A1CYP3A4MEN1KMT2ANPC1
Methoxymethane SCHEMBL28231191 0.86 ALDH1A1 (0.66) ALDH1A1CYP3A4MEN1KMT2ANPC1
SCHEMBL1791859 0.83 NPC1 (0.68) ALDH1A1CYP3A4MEN1KMT2ANPC1
SCHEMBL11294518 0.83 MEN1 (0.55) ALDH1A1CYP3A4MEN1KMT2ANPC1
Propane SCHEMBL28182556 0.83 ALDH1A1 (0.62) ALDH1A1CYP3A4MEN1KMT2ANPC1
Benzophenone SCHEMBL28254452 0.83 ALDH1A1 (0.62) ALDH1A1CYP3A4MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0006254-B1 BENZOIN OXIME DERIVATIVES, PROCESS FOR THEIR PREPARATION, COMPOSITIONS CONTAINING SUCH DERIVATIVES AND METHOD FOR THEIR USE AS FUNGICIDES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1982-12-22 EP disclosed
US-4304789-A Benzoin oxime fungicides SHELL OIL COMPANY (US) 1981-12-08 US disclosed
EP-0006254-A1 Benzoin oxime derivatives, process for their preparation, compositions containing such derivatives and method for their use as fungicides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1980-01-09 EP disclosed