Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 6/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.58 |
| ▸ | NMUR2 | Q9GZQ4 | 5/20 | 0.50 |
| ▸ | NMUR1 | Q9HB89 | 5/20 | 0.50 |
| ▸ | APLNR | P35414 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11289034 | 1.00 | OPRD1 (0.58) | OPRD1OPRM1NMUR2NMUR1APLNR | |
| SCHEMBL31135242 | 0.89 | F2 (0.58) | OPRD1OPRM1NMUR2NMUR1APLNR | |
| SCHEMBL30158799 | 0.89 | OPRM1 (0.59) | OPRD1OPRM1NMUR2NMUR1APLNR | |
| SCHEMBL30785950 | 0.89 | OPRM1 (0.57) | OPRD1OPRM1NMUR2NMUR1APLNR | |
| SCHEMBL30159031 | 0.88 | NMUR2 (0.57) | OPRD1OPRM1NMUR2NMUR1APLNR | |
| SCHEMBL29679668 | 0.87 | SLC6A2 (0.61) | OPRD1OPRM1NMUR2NMUR1 | |
| SCHEMBL29816378 | 0.85 | APLNR (0.64) | OPRM1NMUR2NMUR1APLNR | |
| SCHEMBL31191391 | 0.84 | OPRD1 (0.53) | OPRD1OPRM1NMUR2NMUR1 | |
| SCHEMBL11443809 | 0.84 | SLC6A2 (0.67) | OPRD1OPRM1NMUR2NMUR1 | |
| SCHEMBL30475368 | 0.83 | OPRD1 (0.55) | OPRD1OPRM1NMUR2NMUR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4351828-A | N-Substituted cyclopeptide derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-09-28 | — | — | US | disclosed |
| US-4237045-A | N-substituted cyclopeptide derivatives and preparation thereof | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |