Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.30 |
| ▸ | INSR | P06213 | 1/20 | 0.30 |
| ▸ | IGF1R | P08069 | 1/20 | 0.30 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.30 |
| ▸ | KIT | P10721 | 1/20 | 0.30 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.30 |
| ▸ | FLT1 | P17948 | 1/20 | 0.30 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10925445 | 0.88 | HTR7 (0.40) | MEN1CYP3A4CYP2D6CYP2C9TSHR | |
| SCHEMBL577007 | 0.70 | HTR7 (0.51) | KCNH2HTR7 | |
| SCHEMBL10360942 | 0.70 | HSD11B1 (0.35) | HSD11B1CYP3A4TSHRTAAR1KCNH2 | |
| SCHEMBL576676 | 0.69 | HTR7 (0.52) | MEN1TSHRKMT2AHTR7 | |
| SCHEMBL10360978 | 0.68 | TAAR1 (0.36) | CYP2D6CYP2C19TAAR1HTR7 | |
| SCHEMBL10360827 | 0.66 | HMOX1 (0.35) | TSHR | |
| SCHEMBL9458345 | 0.65 | HSD11B1 (0.38) | HSD11B1MEN1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL11289335 | 0.65 | HTR7 (0.40) | MEN1TSHRKMT2AHTR7 | |
| SCHEMBL11201668 | 0.64 | TAAR1 (0.37) | HSD11B1TAAR1KCNH2FFAR2 | |
| SCHEMBL11068772 | 0.60 | TAAR1 (0.38) | HSD11B1TAAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061910-A2 | Novel substituted imidazoles and triazoles, fungicidal compositions containing them, the use thereof for combating fungi and processes for the preparation of intermediates for making the imidazoles and triazoles | ROHM AND HAAS COMPANY (US) | 1982-10-06 | — | — | EP | disclosed |