Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10460943 | 0.94 | MEN1 (0.52) | KMT2ACRHBPCRHR2L3MBTL1GAA | |
| Bromide SCHEMBL11109409 | 0.92 | MEN1 (0.50) | KMT2ACRHBPCRHR2L3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL11223174 | 0.92 | GAA (0.50) | KMT2ACRHBPCRHR2L3MBTL1GAA | |
| SCHEMBL13701830 | 0.80 | MEN1 (0.55) | KMT2ACRHBPCRHR2L3MBTL1GAA | |
| SCHEMBL11288784 | 0.80 | GPR139 (0.52) | KMT2ACSNK1DL3MBTL1GAAMEN1 | |
| SCHEMBL11433691 | 0.80 | CRHBP (0.61) | KMT2ACRHBPCRHR2GAAHPGD | |
| SCHEMBL11288698 | 0.79 | ATM (0.59) | KMT2ACRHBPCRHR2PKML3MBTL1 | |
| SCHEMBL11489196 | 0.78 | POLB (0.56) | KMT2APKMHPGDMEN1MAPT | |
| SCHEMBL27837335 | 0.78 | GAA (0.49) | KMT2ACRHBPCRHR2L3MBTL1GAA | |
| SCHEMBL16406524 | 0.78 | CRHBP (0.55) | KMT2ACRHBPCRHR2PKMCSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0006298-B1 | ANTI-INFLAMMATORY 1-PHENYL-2-AMINOETHANOL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS THEREOF FOR TOPICAL USE, AND PROCESSES FOR THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-03-31 | — | — | EP | disclosed |
| EP-0006298-A1 | Anti-inflammatory 1-phenyl-2-aminoethanol derivatives, pharmaceutical compositions thereof for topical use, and processes for their manufacture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-01-09 | — | — | EP | disclosed |