SCHEMBL11289148

SCHEMBL11289148

CCCCOc1ccc(CCc2ccccc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.66
CHRNB4 P30926 1/20 0.65
CHRNA3 P32297 1/20 0.65
CHRNA7 P36544 1/20 0.65
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
MEN1 O00255 1/20 0.59
KMT2A Q03164 1/20 0.59
FFAR1 O14842 3/20 0.57
L3MBTL1 Q9Y468 2/20 0.54
LMNA P02545 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27258307 0.91 FFAR1 (0.61) LTA4HCHRNB4CHRNA3CHRNA7NPC1
SCHEMBL13072255 0.91 FFAR1 (0.64) LTA4HCHRNB4CHRNA3CHRNA7NPC1
SCHEMBL13573549 0.91 LTA4H (0.66) LTA4HCHRNB4CHRNA3CHRNA7NPC1
SCHEMBL27629404 0.89 MEN1 (0.59) LTA4HCHRNB4CHRNA3CHRNA7NPC1
SCHEMBL10782297 0.89 LTA4H (0.67) LTA4HCHRNB4CHRNA3CHRNA7NPC1
SCHEMBL16803105 0.89 FFAR1 (0.63) LTA4HCHRNB4CHRNA3CHRNA7NPC1
SCHEMBL7440978 0.88 L3MBTL1 (0.69) LTA4HL3MBTL1
SCHEMBL11667261 0.88 NR5A1 (0.62) LTA4HNPC1RAB9AMEN1KMT2A
SCHEMBL13596220 0.87 FFAR1 (0.64) LTA4HCHRNB4CHRNA3CHRNA7FFAR1
SCHEMBL10970678 0.86 NPC1 (0.65) LTA4HCHRNB4CHRNA3CHRNA7NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0057740-A1 Pressure sensitive recording sheets DIAMOND SHAMROCK CORPORATION (US) 1982-08-18 EP disclosed