Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | LTA4H | P09960 | 16/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570564 | 0.96 | L3MBTL1 (0.70) | L3MBTL1LTA4HCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL18854865 | 0.94 | L3MBTL1 (0.68) | L3MBTL1LTA4HCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL18995913 | 0.94 | L3MBTL1 (0.68) | L3MBTL1LTA4HCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL28676091 | 0.94 | L3MBTL1 (0.68) | L3MBTL1LTA4HCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL18854866 | 0.94 | L3MBTL1 (0.68) | L3MBTL1LTA4HCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2492282 | 0.92 | CYP2D6 (0.59) | L3MBTL1LTA4HCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL11289148 | 0.88 | LTA4H (0.66) | L3MBTL1LTA4H | |
| SCHEMBL8672820 | 0.85 | LTA4H (0.74) | L3MBTL1LTA4HCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1331014 | 0.85 | LTA4H (0.87) | LTA4HCYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL36192 | 0.85 | LTA4H (0.87) | LTA4HCYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128337-A | Hypotensive agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-07 | — | — | US | claimed |
| EP-2060949-A1 | RADIATION-SENSITIVE COMPOSITION AND PROCESS FOR PRODUCING LOW-MOLECULAR COMPOUND FOR USE THEREIN | JSR Corporation (JP) | 2009-05-20 | — | — | EP | disclosed |