Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11287469 | 0.86 | MEN1 (0.47) | KDM4EMEN1KMT2ATDP1PARP1 | |
| Hydrochloric Acid SCHEMBL11086416 | 0.84 | PARP1 (0.51) | KDM4EMEN1KMT2APARP1LMNA | |
| SCHEMBL11076059 | 0.83 | TLR7 (0.48) | KDM4EMEN1KMT2ATDP1PARP1 | |
| SCHEMBL11086406 | 0.81 | PARP1 (0.46) | KDM4EMEN1KMT2APARP1LMNA | |
| SCHEMBL11078271 | 0.81 | PARP1 (0.50) | KDM4EPARP1LMNAALDH1A1HPGD | |
| SCHEMBL11076859 | 0.79 | APP (0.44) | KDM4EPARP1LMNAALDH1A1HPGD | |
| SCHEMBL11080835 | 0.77 | PARP1 (0.46) | KDM4EMEN1KMT2APARP1LMNA | |
| SCHEMBL11081129 | 0.76 | PARP1 (0.48) | KDM4EMEN1KMT2APARP1ALDH1A1 | |
| SCHEMBL11083854 | 0.76 | PARP1 (0.46) | PARP1ADRB2ADORA2A | |
| Hydrochloric Acid SCHEMBL11077145 | 0.75 | PARP1 (0.52) | KDM4EMEN1KMT2APARP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4340607-A | Antimicrobial 3H-naphtho[1,2-d]imidazoles | GRUPPO LEPETIT S.P.A. (IT) | 1982-07-20 | — | — | US | disclosed |
| EP-0012866-A1 | New 3H-naphtho(1,2-d)imidazoles, processes for preparing them, compounds for use as antiinflammatory and antimicrobial agents and compositions for that use containing them | GRUPPO LEPETIT S.P.A. (IT) | 1980-07-09 | — | — | EP | disclosed |