Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11286796 | 0.85 | HTR2A (0.54) | HTR2AHTR2CKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11283943 | 0.82 | HTR2C (0.52) | HTR2AHTR2CKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11288596 | 0.81 | HTR2C (0.53) | HTR2AHTR2CKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL11202515 | 0.79 | MEN1 (0.38) | KDM4EHPGDSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL11200250 | 0.79 | ALDH1A1 (0.37) | KDM4EHPGDSMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL11201344 | 0.77 | PARP1 (0.39) | KDM4EHPGDSMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL11285166 | 0.76 | KDM4E (0.39) | KDM4EHPGDSMN1; SMN2HSD17B10GBA1 | |
| SCHEMBL11285567 | 0.74 | KDM4E (0.41) | HTR2CKDM4EHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL11284746 | 0.73 | HSD17B10 (0.42) | HTR2CKDM4EHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL11288329 | 0.73 | GBA1 (0.53) | HTR2AHTR2CKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |