Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28069712 | 0.87 | FABP5 (0.45) | FABP5TSPOTSHRHTTMEN1 | |
| SCHEMBL208874 | 0.86 | FABP5 (0.41) | FABP5TSPOTSHRHTTMEN1 | |
| SCHEMBL4784032 | 0.85 | FABP5 (0.41) | FABP5TSPOTSHRHTTMEN1 | |
| SCHEMBL1526171 | 0.84 | FABP5 (0.40) | FABP5TSPOTSHRHTTMEN1 | |
| SCHEMBL6298094 | 0.83 | FABP5 (0.42) | FABP5TSPOTSHRHTTMEN1 | |
| SCHEMBL5372417 | 0.82 | FABP5 (0.39) | FABP5TSPOTSHRHTTMEN1 | |
| SCHEMBL5670740 | 0.81 | FABP5 (0.39) | FABP5TSPOTSHRHTTMEN1 | |
| SCHEMBL294203 | 0.81 | FABP5 (0.40) | FABP5TSHRHTTMEN1KMT2A | |
| SCHEMBL3433024 | 0.81 | HSD17B10 (0.39) | FABP5TSHRHTTMEN1KMT2A | |
| SCHEMBL27575610 | 0.81 | FABP5 (0.46) | FABP5TSHRHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282760-A1 | METHOD FOR THE TREATMENT OR PROPHYLAXIS OF CHRONIC INFLAMMATORY DISEASES | Drug Discovery Factory B.V. (NL) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009144279-A1 | METHOD FOR THE TREATMENT OR PROPHYLAXIS OF CHRONIC INFLAMMATORY DISEASES | DRUG DISCOVERY FACTORY B.V. (NL) | 2009-12-03 | — | — | WO | disclosed |
| EP-1252177-A1 | LIGAND FOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR | SUPRATEK PHARMA, INC. (CA) | 2002-10-30 | — | — | EP | disclosed |
| WO-2001057067-A1 | LIGAND FOR VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR | SUPRATEK PHARMA INC. (US) | 2001-08-09 | — | — | WO | disclosed |
| EP-1012247-A1 | SHORT PEPTIDES WHICH SELECTIVELY MODULATE INTRACELLULAR SIGNALLING | The Children's Medical Center Corporation (US) | 2000-06-28 | — | — | EP | disclosed |
| EP-0912195-A1 | VACCINE COMPRISING ANTIGENS BOUND TO CARRIERS THROUGH LABILE BONDS | Stichting Instituut voor Dierhouderij en Diergezondheid (ID-DLO) (NL) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998053051-A1 | SHORT PEPTIDES WHICH SELECTIVELY MODULATE INTRACELLULAR SIGNALLING | THE CHILDREN'S MEDICAL CENTER CORPORATION (US) | 1998-11-26 | — | — | WO | disclosed |
| WO-1997049425-A1 | VACCINE COMPRISING ANTIGENS BOUND TO CARRIERS THROUGH LABILE BONDS | STICHTING INSTITUUT VOOR DIERHOUDERIJ EN DIERGEZONDHEID (NL) | 1997-12-31 | — | — | WO | disclosed |