Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208874 | 0.91 | FABP5 (0.41) | FABP5MEN1KMT2ATSHRHTT | |
| SCHEMBL28069712 | 0.84 | FABP5 (0.45) | FABP5MEN1KMT2ATSHRHTT | |
| SCHEMBL4784032 | 0.83 | FABP5 (0.41) | FABP5MEN1KMT2ATSHRHTT | |
| SCHEMBL1526171 | 0.82 | FABP5 (0.40) | FABP5MEN1KMT2ATSHRHTT | |
| SCHEMBL6298094 | 0.81 | FABP5 (0.42) | FABP5MEN1KMT2ATSHRHTT | |
| SCHEMBL1128931 | 0.81 | FABP5 (0.41) | FABP5MEN1KMT2ATSHRHTT | |
| SCHEMBL5372417 | 0.81 | FABP5 (0.39) | FABP5MEN1KMT2ATSHRHTT | |
| SCHEMBL5670740 | 0.80 | FABP5 (0.39) | FABP5MEN1KMT2ATSHRHTT | |
| SCHEMBL3433024 | 0.79 | HSD17B10 (0.39) | FABP5MEN1KMT2ATSHRHTT | |
| SCHEMBL27575610 | 0.79 | FABP5 (0.46) | FABP5MEN1KMT2ATSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 456 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210138037-A1 | NOVEL APPLICATION OF HEPARIN-BINDING EPIDERMAL GROWTH FACTOR-LIKE GROWTH FACTOR FOR MEDICAL PURPOSES | KAGOSHIMA UNIVERSITY (JP) | 2021-05-13 | — | — | US | disclosed |
| US-10905742-B2 | Application of heparin-binding epidermal growth factor-like growth factor for medical purposes | KAGOSHIMA UNIVERSITY (JP) | 2021-02-02 | — | — | US | disclosed |
| EP-2792745-B1 | MODIFICATION OF HELPER T CELL-INDUCING POLYPEPTIDE | NAT UNIV CORP KOCHI UNIV (JP) | 2017-11-15 | — | — | EP | disclosed |
| EP-2703411-B1 | NANOPARTICLES CONTAINING PH-RESPONSIVE PEPTIDE | TAIHO PHARMACEUTICAL CO LTD (JP) | 2017-10-11 | — | — | EP | disclosed |
| EP-2910564-B1 | WEAKLY ACIDIC PH-RESPONSIVE PEPTIDE AND LIPOSOME CONTAINING SAME | TAIHO PHARMACEUTICAL CO LTD (JP) | 2017-03-22 | — | — | EP | disclosed |
| US-9526791-B2 | Weakly acidic pH-responsive peptide and liposome containing same | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2016-12-27 | — | — | US | disclosed |
| US-9186389-B2 | Nanoparticles containing pH-responsive peptide | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2015-11-17 | — | — | US | disclosed |
| US-20150250893-A1 | WEAKLY ACIDIC pH-RESPONSIVE PEPTIDE AND LIPOSOME CONTAINING SAME | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2015-09-10 | — | — | US | disclosed |
| EP-2910564-A1 | WEAKLY ACIDIC pH-RESPONSIVE PEPTIDE AND LIPOSOME CONTAINING SAME | Taiho Pharmaceutical Co., Ltd. (JP) | 2015-08-26 | — | — | EP | disclosed |
| US-20140341939-A1 | MODIFICATION OF HELPER T CELL-INDUCING POLYPEPTIDE | NATIONAL UNIVERSITY CORPORATION KOCHI UNIVERSITY (JP) | 2014-11-20 | — | — | US | disclosed |
| US-5801147-A | ADMINISTERING A POLYPEPTIDE AS AMIDE, ESTER OR SALT FOR NERVE ACTIVATION AND GASTRIC INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-09-01 | — | — | US | disclosed |
| EP-0824149-A2 | Glutamine: fructose-6-phosphate amidotransferase (GFAT), its production and use | Takeda Chemical Industries, Ltd. (JP) | 1998-02-18 | — | — | EP | disclosed |
| EP-0799892-A2 | Calpain, its production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-08 | — | — | EP | disclosed |
| US-5623050-A | NERVE ACTIVATING AGENT | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0738280-A1 | SUPERACTIVE VIP ANTAGONISTS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-10-23 | — | — | EP | disclosed |
| US-5565424-A | VASOACTIVE INTESTINAL PEPTIDE ANTAGONISTS USEFUL AS ANTITUMOR AND ANTICANCER AGENTS | RAMOT - UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRIAL DEVELOPMENT LTD. (IL) | 1996-10-15 | — | — | US | disclosed |
| WO-1995021194-A1 | SUPERACTIVE VIP ANTAGONISTS | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-08-10 | — | — | WO | disclosed |
| EP-0620008-A1 | Use of vip, analogues and fragments thereof for the treatment of neurodegenerative diseases | YEDA RESEARCH AND DEVELOPMENT COMPANY, LTD. (IL) | 1994-10-19 | — | — | EP | disclosed |
| EP-0540969-A2 | Derivatives of structurally modified VIP and pharmaceutical compositions containing them | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1993-05-12 | — | — | EP | disclosed |
| EP-0529487-A2 | PACAP derivatives having c-AMP producing activity | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-03-03 | — | — | EP | disclosed |