Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | FYN | P06241 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10848173 | 0.82 | LMNA (0.43) | LMNASMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL10848167 | 0.82 | LMNA (0.43) | LMNASMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL20144709 | 0.80 | GAA (0.62) | LMNAKMT2AMEN1ALDH1A1NPSR1 | |
| Hydrochloric Acid SCHEMBL10847832 | 0.80 | CYP2D6 (0.41) | LMNASMN1; SMN2KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10847829 | 0.80 | CYP2D6 (0.41) | LMNASMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL20144686 | 0.79 | GAA (0.64) | LMNAKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL11291642 | 0.77 | ADRA2C (0.41) | LMNASMN1; SMN2KMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10847654 | 0.76 | LMNA (0.42) | LMNASMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL4380710 | 0.75 | GAA (0.59) | LMNAKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL11661410 | 0.70 | HPGD (0.67) | LMNASMN1; SMN2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0066919-A1 | 4-Alkyl-thiophenyl-ethanolamines, having an activity on the cerebral circulation, the blood platelet-aggregation and the lipemia | MAGGIONI FARMACEUTICI S.p.A. (IT) | 1982-12-15 | — | — | EP | claimed |