SCHEMBL11289339

SCHEMBL11289339

COc1c(N)cc(C)cc1S(=O)(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 3/20 0.41
GAA P10253 2/20 0.38
MAPT P10636 2/20 0.38
LMNA P02545 2/20 0.38
ACHE P22303 1/20 0.36
CYP3A4 P08684 1/20 0.36
PKM P14618 1/20 0.36
F2 P00734 1/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
POLB P06746 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
RECQL P46063 1/20 0.36
CASP6 P55212 1/20 0.36
ELAVL1 Q15717 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10482234 0.84 ALDH1A1 (0.42) ALDH1A1KDM4EGAAMAPTPKM
SCHEMBL9358421 0.82 ALDH1A1 (0.45) ALDH1A1KDM4EGAAMAPTPKM
SCHEMBL18700928 0.81 F2 (0.41) ALDH1A1KDM4ELMNAACHEPKM
SCHEMBL10882114 0.81 F2 (0.40) ALDH1A1KDM4EGAACYP3A4PKM
SCHEMBL11038082 0.77 ALDH1A1 (0.47) ALDH1A1KDM4EGAAMAPTLMNA
SCHEMBL8500961 0.77 ALDH1A1 (0.54) ALDH1A1KDM4EGAAMAPTLMNA
SCHEMBL29239042 0.77 ALDH1A1 (0.52) ALDH1A1KDM4EGAAMAPTLMNA
SCHEMBL11405629 0.77 PKM (0.33) ALDH1A1PKMCASP6TTRCTDSP1
SCHEMBL4621087 0.76 ACHE (0.52) ALDH1A1KDM4EGAAMAPTLMNA
SCHEMBL10431756 0.76 ALDH1A1 (0.45) ALDH1A1KDM4EGAAMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116157109-A Oral pharmaceutical preparation 国立大学法人大阪大学 2023-05-23 CN disclosed
EP-0066714-A2 Reactive dyestuffs BASF Aktiengesellschaft (DE) 1982-12-15 EP disclosed
US-4166069-A PROCESS FOR THE PREPARATION OF 2-METHOXY-5-METHYLANILINE-4-SULPHONIC ACID BAYER AKTIENGESELLSCHAFT (DE) 1979-08-28 US disclosed