Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 8/20 | 0.56 |
| ▸ | NOS2 | P35228 | 8/20 | 0.56 |
| ▸ | NOS3 | P29474 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | PNMT | P11086 | 1/20 | 0.54 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17230076 | 0.89 | GRIN2B (0.48) | NOS1NOS2NOS3ALDH1A1SMN1; SMN2 | |
| SCHEMBL22273431 | 0.81 | ALDH1A1 (0.35) | NOS1NOS2NOS3ALDH1A1SMN1; SMN2 | |
| SCHEMBL11296929 | 0.81 | HRH3 (0.50) | NOS1NOS2NOS3LOXL2 | |
| SCHEMBL36008 | 0.81 | LOXL2 (0.71) | NOS1NOS2NOS3ALDH1A1SMN1; SMN2 | |
| SCHEMBL10422276 | 0.81 | LOXL2 (0.71) | NOS1NOS2NOS3ALDH1A1SMN1; SMN2 | |
| SCHEMBL18758459 | 0.78 | GRIN2D (0.45) | NOS1NOS2NOS3ALDH1A1SMN1; SMN2 | |
| SCHEMBL19979553 | 0.78 | MAOB (0.52) | ALDH1A1CYP3A4GRIN2DGRIN3BGRIN1 | |
| SCHEMBL25576222 | 0.78 | MGLL (0.43) | NOS1NOS2NOS3ALDH1A1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL6899866 | 0.78 | LOXL2 (0.67) | NOS1NOS2NOS3ALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8195914 | 0.78 | LOXL2 (0.67) | NOS1NOS2NOS3ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0000815-B1 | PROCESS FOR PREPARING N-ARYL OR N-ARALKYL SUBSTITUTED URETHANES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1982-01-27 | — | — | EP | disclosed |
| US-4227008-A | CATALYTIC REACTION OF A NITRO-, NITROSO-, OR CARBAMATE-CONTAINING AROMATIC PRIMARY AMINE, AN ALCOHOL, AND CARBON MONOXIDE | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1980-10-07 | — | — | US | disclosed |
| EP-0000815-A1 | Process for preparing N-aryl or N-aralkyl substituted urethanes | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1979-02-21 | — | — | EP | disclosed |