Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291070 | 0.86 | NPC1 (0.48) | KDM4EMAPTALOX15ALDH1A1HSD17B10 | |
| SCHEMBL11328223 | 0.85 | LMNA (0.49) | MAPTALDH1A1HSD17B10HPGDRECQL | |
| SCHEMBL11296742 | 0.83 | TDP1 (0.43) | KDM4EMAPTALOX15ALDH1A1HSD17B10 | |
| SCHEMBL11293489 | 0.82 | KDM4E (0.56) | KDM4EMAPTALOX15ALDH1A1HSD17B10 | |
| SCHEMBL11287507 | 0.81 | GAA (0.47) | KDM4EMAPTALOX15ALDH1A1HSD17B10 | |
| SCHEMBL11294809 | 0.80 | TDP1 (0.44) | MAPTALDH1A1RECQLKMT2AMAPK1 | |
| SCHEMBL11297259 | 0.80 | POLB (0.45) | MAPTALDH1A1RECQLKMT2AMAPK1 | |
| SCHEMBL11296539 | 0.80 | MAPT (0.49) | KDM4EMAPTALOX15ALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL11289242 | 0.79 | POLB (0.44) | MAPTKMT2AMAPK1POLBTDP1 | |
| Hydrochloric Acid SCHEMBL11288940 | 0.79 | MAPT (0.47) | KDM4EMAPTALOX15ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |