Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10977242 | 0.89 | CA2 (0.36) | POLBCA2HTTHTR1AADRA2A | |
| SCHEMBL10980338 | 0.89 | CA2 (0.36) | POLBCA2HTTHTR1AADRA2A | |
| SCHEMBL10975287 | 0.76 | CA2 (0.44) | POLBCA2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL10975682 | 0.76 | CA2 (0.44) | POLBCA2LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9526092 | 0.71 | AHR (0.41) | CA2ADRA1A | |
| SCHEMBL4333283 | 0.70 | CA2 (0.45) | POLBPARP1CA2HTTHTR1A | |
| SCHEMBL3632741 | 0.70 | CA2 (0.45) | POLBPARP1CA2HTTLMNA | |
| SCHEMBL7621497 | 0.69 | ABCB1 (0.38) | HTR1AADRA2ADRD1TBXA2RSLC6A2 | |
| SCHEMBL9481539 | 0.67 | CA2 (0.38) | CA2ADRA1A | |
| SCHEMBL9482152 | 0.67 | CA2 (0.38) | CA2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4309349-A | Stereospecific process for preparing epoxybenzodioxans | CIBA-GEIGY CORPORATION (US) | 1982-01-05 | — | — | US | disclosed |
| US-4261907-A | Stereospecific process | CIBA-GEIGY CORPORATION (US) | 1981-04-14 | — | — | US | disclosed |
| US-4212808-A | CONDENSING 2,3-BIS-HALOMETHYLOXIRANE AND SLATS OR CATECHOL | CIBA-GEIGY CORPORATION (US) | 1980-07-15 | — | — | US | disclosed |