Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9526535 | 0.80 | AKR1B1 (0.32) | AKR1B1SLC5A2 | |
| SCHEMBL9482152 | 0.78 | CA2 (0.38) | CA2ADRA1DADRA1AADRA1B | |
| SCHEMBL9525389 | 0.78 | MAP3K14 (0.35) | SLC5A2 | |
| SCHEMBL9481539 | 0.78 | CA2 (0.38) | CA2ADRA1DADRA1AADRA1B | |
| SCHEMBL10980338 | 0.75 | CA2 (0.36) | CA2ADRA1A | |
| SCHEMBL10977242 | 0.75 | CA2 (0.36) | CA2ADRA1A | |
| SCHEMBL9526205 | 0.74 | DPP4 (0.42) | ADRA1DADRA1AADRA1B | |
| SCHEMBL29444744 | 0.73 | CA2 (0.46) | AHRCA2ADRA1DADRA1AADRA1B | |
| SCHEMBL11003287 | 0.73 | CA2 (0.46) | AHRCA2ADRA1DADRA1AADRA1B | |
| SCHEMBL6982180 | 0.73 | CA2 (0.59) | AHRCA2ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0359290-B1 | AROMATIC DIOLS | GLAXO GROUP LIMITED (GB) | 1993-08-04 | — | — | EP | claimed |
| EP-0359290-A1 | Aromatic diols | GLAXO GROUP LIMITED (GB) | 1990-03-21 | — | — | EP | claimed |
| EP-0359290-B1 | AROMATIC DIOLS | GLAXO GROUP LIMITED (GB) | 1993-08-04 | — | — | EP | disclosed |
| EP-0162593-B1 | HETEROCYCLIC AMINO COMPOUNDS | GLAXO GROUP LIMITED (GB) | 1990-08-16 | — | — | EP | disclosed |
| EP-0359290-A1 | Aromatic diols | GLAXO GROUP LIMITED (GB) | 1990-03-21 | — | — | EP | disclosed |
| US-4880801-A | ALPHA 2-ADRENORECEPTOR ANTAGONIST | GLAXO GROUP LIMITED (GB) | 1989-11-14 | — | — | US | disclosed |
| EP-0162593-A1 | Heterocyclic amino compounds | GLAXO GROUP LIMITED (GB) | 1985-11-27 | — | — | EP | disclosed |