Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.32 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9481539 | 1.00 | CA2 (0.38) | CA2L3MBTL1MAPK1ADRA1DADRA1A | |
| SCHEMBL9525389 | 0.81 | MAP3K14 (0.35) | HPGD | |
| SCHEMBL9526215 | 0.80 | SLC5A2 (0.31) | — | |
| SCHEMBL9526092 | 0.78 | AHR (0.41) | CA2ADRA1DADRA1AADRA1B | |
| SCHEMBL10980338 | 0.75 | CA2 (0.36) | CA2ADRA1A | |
| SCHEMBL10977242 | 0.75 | CA2 (0.36) | CA2ADRA1A | |
| SCHEMBL1021052 | 0.74 | ADRA1A (0.47) | CA2L3MBTL1MAPK1ADRA1DADRA1A | |
| SCHEMBL9526205 | 0.74 | DPP4 (0.42) | ADRA1DADRA1AADRA1BHPGD | |
| SCHEMBL8125243 | 0.74 | CA2 (0.58) | CA2L3MBTL1MAPK1ADRA1AHPGD | |
| SCHEMBL6974656 | 0.74 | ADRA1A (0.47) | CA2L3MBTL1MAPK1ADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532100-A1 | Benzodioxinopyrrole derivative as alpha 2-adrenoreceptor antagonist | GLAXO GROUP LIMITED (GB) | 1993-03-17 | — | — | EP | disclosed |
| US-5190967-A | Sexual dysfunction | GLAXO GROUP LIMITED (GB) | 1993-03-02 | — | — | US | disclosed |