Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 4/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 6/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16712277 | 0.82 | ALDH1A1 (0.56) | ALDH1A1DAOPOLBPKMTP53 | |
| SCHEMBL16712269 | 0.82 | DAO (0.56) | ALDH1A1DAOPOLBPKMTP53 | |
| SCHEMBL1444085 | 0.79 | PNMT (0.61) | PNMTITGB3ITGA2BTPSAB1TPSD1 | |
| SCHEMBL6421249 | 0.78 | ALDH1A1 (0.65) | PNMTITGB3ITGA2BALDH1A1DAO | |
| Hydrochloric Acid SCHEMBL1443367 | 0.78 | PNMT (0.60) | PNMTITGB3ITGA2BTPSAB1TPSD1 | |
| SCHEMBL15071934 | 0.75 | PNMT (0.54) | PNMTITGB3ITGA2BTPSAB1TPSD1 | |
| SCHEMBL18822929 | 0.75 | PNMT (0.54) | PNMTITGB3ITGA2BTPSAB1TPSD1 | |
| SCHEMBL9471965 | 0.75 | PNMT (0.54) | PNMTITGB3ITGA2BALDH1A1TPSAB1 | |
| Hydrochloric Acid SCHEMBL14141606 | 0.74 | PNMT (0.52) | PNMTITGB3ITGA2BTPSAB1TPSD1 | |
| SCHEMBL4397849 | 0.72 | PNMT (0.61) | PNMTITGB3ITGA2BTPSAB1TPSD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058341-A1 | Azepine derivatives, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1982-08-25 | — | — | EP | disclosed |