Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 6/20 | 0.61 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 5/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 3/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1443367 | 0.98 | PNMT (0.60) | PNMTTPSAB1TPSD1TPSG1ITGB3 | |
| SCHEMBL4058720 | 0.85 | PNMT (0.46) | PNMTTPSAB1TPSD1TPSG1ABCB11 | |
| SCHEMBL18822929 | 0.84 | PNMT (0.54) | PNMTTPSAB1TPSD1TPSG1ITGB3 | |
| SCHEMBL9471965 | 0.84 | PNMT (0.54) | PNMTTPSAB1TPSD1TPSG1ITGB3 | |
| SCHEMBL15071934 | 0.84 | PNMT (0.54) | PNMTTPSAB1TPSD1TPSG1ITGB3 | |
| Hydrochloric Acid SCHEMBL14141606 | 0.83 | PNMT (0.52) | PNMTTPSAB1TPSD1TPSG1ITGB3 | |
| SCHEMBL30536685 | 0.80 | PNMT (0.49) | PNMTTPSAB1TPSD1TPSG1ITGB3 | |
| SCHEMBL4397849 | 0.79 | PNMT (0.61) | PNMTTPSAB1TPSD1TPSG1ITGB3 | |
| SCHEMBL11289658 | 0.79 | PNMT (0.47) | PNMTTPSAB1TPSD1TPSG1ITGB3 | |
| SCHEMBL1038858 | 0.76 | PNMT (0.56) | PNMTTPSAB1TPSD1TPSG1ITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311907-B | Preparation method of high-purity prasugrel | 吉瑞工厂 | 2022-09-13 | — | — | CN | claimed |
| WO-2011029456-A1 | A PROCESS FOR MAKING PRASUGREL AND ITS INTERMEDIATES | SYNTHON BV (NL) | 2011-03-17 | — | — | WO | claimed |
| CN-109311907-B | Preparation method of high-purity prasugrel | 吉瑞工厂 | 2022-09-13 | — | — | CN | disclosed |
| US-10000506-B2 | Optically active 2-hydroxy tetrahydrothienopyridine derivatives, preparation method and use in manufacture of medicament thereof | JIANGSU VCARE PHARMATECH CO., LTD. (CN) | 2018-06-19 | — | — | US | disclosed |
| US-10000506-B2 | Optically active 2-hydroxy tetrahydrothienopyridine derivatives, preparation method and use in manufacture of medicament thereof | JIANGSU VCARE PHARMATECH CO., LTD. (CN) | 2018-06-19 | — | — | US | disclosed |
| EP-2532668-B1 | OPTICALLY ACTIVE 2-HYDROXY TETRAHYDROTHIENOPYRIDINE DERIVATIVES, PREPARATION METHOD AND USE IN MANUFACTURE OF MEDICAMENT THEREOF | JIANGSU VCARE PHARMATECH CO LTD (CN) | 2017-05-24 | — | — | EP | disclosed |
| US-20170121341-A1 | OPTICALLY ACTIVE 2-HYDROXY TETRAHYDROTHIENOPYRIDINE DERIVATIVES, PREPARATION METHOD AND USE IN MANUFACTURE OF MEDICAMENT THEREOF | JIANGSU VCARE PHARMATECH CO., LTD. (CN) | 2017-05-04 | — | — | US | disclosed |
| US-20170121341-A1 | OPTICALLY ACTIVE 2-HYDROXY TETRAHYDROTHIENOPYRIDINE DERIVATIVES, PREPARATION METHOD AND USE IN MANUFACTURE OF MEDICAMENT THEREOF | JIANGSU VCARE PHARMATECH CO., LTD. (CN) | 2017-05-04 | — | — | US | disclosed |
| US-9169265-B2 | Process for preparing pharmaceutical compounds and intermediate compounds | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2015-10-27 | — | — | US | disclosed |
| US-9169265-B2 | Process for preparing pharmaceutical compounds and intermediate compounds | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2015-10-27 | — | — | US | disclosed |
| US-20130030183-A1 | PROCESS FOR PREPARING A PHARMACEUTICAL COMPOUND | EGIS GYOGYSZERGYAR NYILVANOSAN MUKODO RESZVENYTARSASAG (HU) | 2013-01-31 | — | — | US | disclosed |
| WO-2011029456-A1 | A PROCESS FOR MAKING PRASUGREL AND ITS INTERMEDIATES | SYNTHON BV (NL) | 2011-03-17 | — | — | WO | disclosed |
| US-20100261908-A1 | PROCESSES FOR THE PREPARATION OF PRASUGREL , AND ITS SALTS AND POLYMORPHS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-10-14 | — | — | US | disclosed |
| US-20100261908-A1 | PROCESSES FOR THE PREPARATION OF PRASUGREL , AND ITS SALTS AND POLYMORPHS | DR. REDDY'S LABORATORIES LTD. (IN) | 2010-10-14 | — | — | US | disclosed |
| US-20100179184-A1 | ARTICLE OF MANUFACTURE FOR PRASUGREL | ELI LILLY AND COMPANY | 2010-07-15 | — | — | US | disclosed |
| US-20100179184-A1 | ARTICLE OF MANUFACTURE FOR PRASUGREL | ELI LILLY AND COMPANY | 2010-07-15 | — | — | US | disclosed |
| EP-2205611-A2 | PROCESSES FOR THE PREPARATION OF PRASUGREL, AND ITS SALTS AND POLYMORPHS | Dr. Reddy's Laboratories Ltd. (IN) | 2010-07-14 | — | — | EP | disclosed |
| WO-2009122440-A1 | PROCESS FOR THE PREPARATION OF 2-ACETOXY-5-(α -CYCLOPRPYLCARBONYL -2-FLUOROBENZYL)-4,5,6,7-TETRAHYDROTHIENO[3,2-C]PYRIDINE | TORRENT PHARMACEUTICALS LTD. (IN) | 2009-10-08 | — | — | WO | disclosed |
| WO-2009062044-A2 | PROCESSES FOR THE PREPARATION OF PRASUGREL, AND ITS SALTS AND POLYMORPHS | DR. REDDY'S LABORATORIES LTD. (IN) | 2009-05-14 | — | — | WO | disclosed |
| US-20080176893-A1 | Formulation of a Thienopyridine Platelet Aggregation Inhibitor | ELI LILLY AND COMPANY (US) | 2008-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10000506-B2 | Optically active 2-hydroxy tetrahydrothienopyridine derivatives, preparation method and use in manufacture of medicament thereof | TFPI, DHPS, THPO | PNMT 172/4885TPSAB1 141/4885TPSD1 125/4885 |
| US-20130030183-A1 | PROCESS FOR PREPARING A PHARMACEUTICAL COMPOUND | CYP3A5, CYP2C19, CYP4B1 | PNMT 1623/4885TPSAB1 246/4885TPSD1 610/4885 |
| US-20080176893-A1 | Formulation of a Thienopyridine Platelet Aggregation Inhibitor | TBXA2R, THPO, PFKP | PNMT 372/4885TPSAB1 105/4885TPSD1 228/4885 |
| US-20100261908-A1 | PROCESSES FOR THE PREPARATION OF PRASUGREL , AND ITS SALTS AND POLYMORPHS | PFKP, CYP2C19, CYP2C9 | PNMT 3754/4885TPSAB1 1704/4885TPSD1 1443/4885 |
| US-20170121341-A1 | OPTICALLY ACTIVE 2-HYDROXY TETRAHYDROTHIENOPYRIDINE DERIVATIVES, PREPARATION METHOD AND USE IN MANUFACTURE OF MEDICAMENT THEREOF | TFPI, DHPS, THPO | PNMT 172/4885TPSAB1 141/4885TPSD1 125/4885 |
| US-20100179184-A1 | ARTICLE OF MANUFACTURE FOR PRASUGREL | PFKP, PTGIS, P2RY6 | PNMT 3136/4885TPSAB1 2097/4885TPSD1 2279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.