Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 5/20 | 0.39 |
| ▸ | CES1 | P23141 | 7/20 | 0.38 |
| ▸ | FAAH | O00519 | 4/20 | 0.38 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | PPARD | Q03181 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11293412 | 0.92 | CES2 (0.45) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL7496380 | 0.82 | HSD17B10 (0.44) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL1276540 | 0.81 | CES2 (0.47) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL7855736 | 0.80 | EPHX1 (0.43) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL3062027 | 0.80 | ALDH1A1 (0.35) | ALDH1A1TDP1 | |
| SCHEMBL6907432 | 0.79 | HSD17B10 (0.50) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL10529861 | 0.79 | HSD17B10 (0.50) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL11305316 | 0.78 | CES2 (0.44) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL8777414 | 0.78 | EPHX1 (0.48) | CES2HSD17B10GMNNTP53POLB | |
| SCHEMBL11544996 | 0.78 | EPHX1 (0.48) | CES2HSD17B10GMNNTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4311647-A | Process for preparation of (hydrocarbonthio)oxamides | THE B. F. GOODRICH COMPANY (US) | 1982-01-19 | — | — | US | disclosed |