Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12619427 | 0.82 | ALDH1A1 (0.43) | MAPK1LMNAALDH1A1PDK1PKM | |
| SCHEMBL27918543 | 0.78 | ALDH1A1 (0.58) | TSHRLMNAALDH1A1CYP1A2MEN1 | |
| SCHEMBL27489083 | 0.78 | TSHR (0.46) | MAPK1TSHRLMNAALDH1A1PDK1 | |
| SCHEMBL27778996 | 0.77 | PDK1 (0.49) | MAPK1TSHRLMNAALDH1A1PDK1 | |
| SCHEMBL624054 | 0.77 | ALDH1A1 (0.64) | MAPK1TSHRLMNAALDH1A1PDK1 | |
| SCHEMBL14267713 | 0.77 | HSD17B10 (0.49) | MAPK1LMNAALDH1A1PKMMEN1 | |
| SCHEMBL5150129 | 0.76 | MAPK1 (0.50) | MAPK1TSHRALDH1A1PDK1VCAM1 | |
| SCHEMBL5996591 | 0.76 | MAPK1 (0.50) | MAPK1TSHRALDH1A1PDK1VCAM1 | |
| SCHEMBL5996588 | 0.76 | MAPK1 (0.50) | MAPK1TSHRALDH1A1PDK1VCAM1 | |
| SCHEMBL27654745 | 0.76 | PDK1 (0.49) | MAPK1TSHRLMNAALDH1A1PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0008759-B1 | NEW PROCESS FOR PREPARING AN 1H-INDAZOL-3-YLACETIC ACID DERIVATIVE | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |
| EP-0008759-A2 | New process for preparing an 1H-indazol-3-ylacetic acid derivative | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1980-03-19 | — | — | EP | disclosed |