Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11282410 | 0.87 | ALOX15 (0.55) | ALOX15TOP2AKMT2ARAB9ANPC1 | |
| SCHEMBL11281184 | 0.87 | ALOX15 (0.55) | ALOX15TOP2AKMT2ARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL11636402 | 0.85 | ALOX15 (0.55) | ALOX15TOP2AKMT2AMEN1RAB9A | |
| SCHEMBL11631275 | 0.79 | ALDH1A1 (0.49) | ALDH1A1RAB9AKDM4EGAATSHR | |
| SCHEMBL11281656 | 0.79 | ALOX15 (0.51) | ALOX15KMT2AMEN1ALDH1A1RAB9A | |
| SCHEMBL11283335 | 0.79 | TOP2A (0.36) | ALOX15TOP2AKMT2AMEN1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11633271 | 0.78 | ADRB2 (0.50) | ALDH1A1RAB9AKDM4EGAATSHR | |
| SCHEMBL11289720 | 0.78 | ALOX15 (0.47) | ALOX15TOP2A | |
| SCHEMBL11288199 | 0.78 | ALOX15 (0.44) | ALOX15TOP2AKMT2AMEN1ALDH1A1 | |
| SCHEMBL11291983 | 0.78 | ALOX15 (0.37) | ALOX15TOP2AKMT2AALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |