Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | CPT1A | P50416 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15256797 | 1.00 | ABCB11 (0.73) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL15258345 | 0.86 | ABCB11 (0.78) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL11298608 | 0.86 | ABCB11 (0.77) | ABCB11LMNAMAPTMAPK1CPT1A | |
| Rac-Etomoxir SCHEMBL681359 | 0.84 | ABCB11 (1.00) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL11272688 | 0.84 | ABCB11 (0.52) | ABCB11LMNAMAPTMAPK1GAA | |
| Etomoxir SCHEMBL49075 | 0.84 | ABCB11 (1.00) | ABCB11LMNAMAPTMAPK1CPT1A | |
| SCHEMBL954683 | 0.84 | ABCB11 (1.00) | ABCB11LMNAMAPTMAPK1CPT1A | |
| Rac-Etomoxir SCHEMBL15256787 | 0.84 | ABCB11 (1.00) | ABCB11LMNAMAPTMAPK1CPT1A | |
| Etomoxir SCHEMBL5883664 | 0.83 | MAPT (0.98) | ABCB11LMNAMAPTMAPK1CPT1A | |
| Etomoxir SCHEMBL12813827 | 0.83 | MAPT (0.98) | ABCB11LMNAMAPTMAPK1CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337267-A | HYPOKETONEMIC, HYPOGLYCEMIC, ANTIDIABETIC | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1982-06-29 | — | — | US | disclosed |