Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TNFRSF1A | P19438 | 4/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291114 | 0.91 | MEN1 (0.44) | NR1H2NR1H3MAPTALDH1A1KMT2A | |
| SCHEMBL11285075 | 0.90 | MEN1 (0.38) | NR1H2NR1H3MAPTALDH1A1KMT2A | |
| SCHEMBL11280457 | 0.83 | CHRM2 (0.35) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL11282576 | 0.82 | MEN1 (0.49) | NR1H2NR1H3MAPTALDH1A1KMT2A | |
| SCHEMBL11290119 | 0.76 | ALDH1A1 (0.33) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL11287708 | 0.76 | ALDH1A1 (0.36) | MAPTALDH1A1KMT2AMEN1KDM4C | |
| SCHEMBL11282135 | 0.74 | MEN1 (0.40) | NR1H2NR1H3MAPTALDH1A1KMT2A | |
| SCHEMBL11280464 | 0.74 | MEN1 (0.32) | KMT2AMEN1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL11289589 | 0.71 | CES1 (0.33) | MAPTALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL11285526 | 0.68 | CASP3 (0.35) | MAPTALDH1A1KMT2AMEN1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4349618-A | 5-DIPHENYLMETHYLENE- OR 5-(FLUOREN-9-YLIDENE) THIOBARBITURIC ACID AND DERIVATIVES AS SENSITIZERS FOR N-VVINYLCARBAZOLE POLYMERS; ELECTROPHORESIS | FUJI PHOTO FILM CO., LTD. (JP) | 1982-09-14 | — | — | US | disclosed |