SCHEMBL11280464

SCHEMBL11280464

CSN1C(=O)C(=C2c3ccccc3-c3c(Cl)cc(Cl)cc32)C(=O)N(SC)C1=O

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
HPGD P15428 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
CYP1A1 P04798 1/20 0.32
CYP1A2 P05177 1/20 0.32
STK10 O94804 2/20 0.32
SLK Q9H2G2 2/20 0.32
CLK2 P49760 1/20 0.32
GSK3A P49840 1/20 0.32
GSK3B P49841 1/20 0.32
S100A4 P26447 1/20 0.31
DPP4 P27487 1/20 0.31
DPP8 Q6V1X1 1/20 0.31
DPP9 Q86TI2 1/20 0.31
PTPRC P08575 1/20 0.30
NTRK1 P04629 1/20 0.30
CHRM2 P08172 1/20 0.30
ADRA2A P08913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11289615 0.90 CES1 (0.32)
SCHEMBL11285099 0.89 S100A4 (0.34) S100A4DPP4DPP8DPP9
SCHEMBL11290119 0.86 ALDH1A1 (0.33) MEN1KMT2AHPGDNPSR1CYP1A1
SCHEMBL11285537 0.81 CDC25B (0.36) MEN1KMT2AHPGDSMN1; SMN2NPSR1
SCHEMBL11280457 0.77 CHRM2 (0.35) MEN1KMT2AHPGDSMN1; SMN2CYP1A1
SCHEMBL11285080 0.76 DPP4 (0.35) S100A4DPP4DPP8DPP9
SCHEMBL11285155 0.74 PGR (0.33) STK10SLKCLK2GSK3AGSK3B
SCHEMBL11291117 0.74 CES1 (0.33) DPP4DPP8DPP9
SCHEMBL11290117 0.74 NR1H2 (0.39) MEN1KMT2AHPGDSMN1; SMN2NPSR1
SCHEMBL11285507 0.73 MEN1 (0.39) MEN1KMT2AS100A4PTPRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4349618-A 5-DIPHENYLMETHYLENE- OR 5-(FLUOREN-9-YLIDENE) THIOBARBITURIC ACID AND DERIVATIVES AS SENSITIZERS FOR N-VVINYLCARBAZOLE POLYMERS; ELECTROPHORESIS FUJI PHOTO FILM CO., LTD. (JP) 1982-09-14 US disclosed