Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718347 | 0.83 | PARP1 (0.46) | GAAPARP1MAPTALDH1A1MAPK1 | |
| SCHEMBL10712387 | 0.79 | CA12 (0.59) | GAAMAPTALDH1A1MAPK1NPC1 | |
| SCHEMBL10258872 | 0.72 | MET (0.47) | GAAMAPTALDH1A1MAPK1NPC1 | |
| SCHEMBL28748453 | 0.71 | KMT2A (0.50) | GAAMAPTALDH1A1MAPK1NPC1 | |
| SCHEMBL519514 | 0.71 | PDE10A (0.53) | GAAMAPTALDH1A1MAPK1NPC1 | |
| SCHEMBL70479 | 0.71 | MAPT (0.69) | GAAMAPTALDH1A1MAPK1NPC1 | |
| SCHEMBL28748461 | 0.69 | ALDH1A1 (0.58) | GAAALDH1A1MAPK1RAB9AKDM4E | |
| SCHEMBL518611 | 0.68 | NR1I2 (0.41) | GAAMAPTALDH1A1MAPK1NPC1 | |
| SCHEMBL10258727 | 0.68 | NR1I2 (0.41) | GAAMAPTALDH1A1MAPK1NPC1 | |
| SCHEMBL13982921 | 0.67 | PARP1 (0.52) | PARP1ALDH1A1KDM4EALOX15SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0049971-A1 | Substituted pyridazines, processes for making them, their use as plant growth regulators, and plant growth regulating compositions containing them | ROHM AND HAAS COMPANY (US) | 1982-04-21 | — | — | EP | disclosed |