Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | PLAT | P00750 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 6/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290343 | 1.00 | NPC1 (0.47) | NPC1MAPTRAB9AMAPK1HSP90AA1 | |
| SCHEMBL17899567 | 0.84 | DRD3 (0.50) | NPC1MAPTRAB9AMAPK1HSP90AA1 | |
| SCHEMBL21028263 | 0.81 | MAPT (0.65) | NPC1MAPTRAB9AMAPK1HSP90AA1 | |
| SCHEMBL10977635 | 0.81 | MAPT (0.65) | NPC1MAPTRAB9AMAPK1HSP90AA1 | |
| SCHEMBL10977632 | 0.81 | MAPT (0.65) | NPC1MAPTRAB9AMAPK1HSP90AA1 | |
| SCHEMBL11282830 | 0.80 | MAPT (0.44) | NPC1MAPTRAB9AMAPK1HSP90AA1 | |
| SCHEMBL11282829 | 0.80 | MAPT (0.44) | NPC1MAPTRAB9AMAPK1HSP90AA1 | |
| SCHEMBL18415114 | 0.77 | MAPT (0.57) | NPC1MAPTRAB9AMAPK1HSP90AA1 | |
| SCHEMBL10977516 | 0.77 | MAPT (0.57) | NPC1MAPTRAB9AMAPK1HSP90AA1 | |
| SCHEMBL10977512 | 0.77 | MAPT (0.57) | NPC1MAPTRAB9AMAPK1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4354976-A | Process for the preparation of azidobenzal compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-10-19 | — | — | US | disclosed |