Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | PRNP | P04156 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | EDNRB | P24530 | 1/20 | 0.47 |
| ▸ | EDNRA | P25101 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1964733 | 0.81 | NAMPT (0.72) | NAMPTPKMKDM4EKMT2AMEN1 | |
| SCHEMBL6602234 | 0.78 | USP2 (0.69) | CA12CA2CA9PKMKMT2A | |
| SCHEMBL17538515 | 0.75 | CYP1A2 (0.55) | CA12CA2CA9PKMKDM4E | |
| Benzene SCHEMBL28205648 | 0.73 | KDM4E (0.96) | NAMPTPKMKDM4EKMT2ANPC1 | |
| SCHEMBL8252530 | 0.72 | ALDH1A1 (0.72) | CA12CA2CA9PKMKDM4E | |
| SCHEMBL3048657 | 0.71 | SMN1; SMN2 (0.59) | NAMPTPKMKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL2058331 | 0.71 | ALDH1A1 (0.68) | CA12CA2CA9PKMKMT2A | |
| SCHEMBL13847546 | 0.71 | KMT2A (0.67) | NAMPTPKMKDM4EKMT2ANPC1 | |
| SCHEMBL211260 | 0.71 | KMT2A (0.61) | CA12CA2CA9PKMKDM4E | |
| SCHEMBL192563 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57183768-A | — | — | None | — | — | JP | disclosed |
| JP-S57183768-A | 4-METHYL-5-(O-CARBOXYPHENYL)CARBAMOYLTHIAZOLE DERIVATIVE AND ITS PREPARATION | KANTO ISHI PHARMA CO LTD | 1982-11-12 | — | — | JP | disclosed |