Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | DHODH | Q02127 | 1/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | PRNP | P04156 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA2 | P00918 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10481401 | 0.89 | KMT2A (0.60) | ALDH1A1KMT2AMEN1PKMDHODH | |
| SCHEMBL14398957 | 0.89 | NPSR1 (0.63) | ALDH1A1KMT2AMEN1PKMDHODH | |
| SCHEMBL14398138 | 0.89 | NPSR1 (0.68) | ALDH1A1KMT2AMEN1PKMDHODH | |
| SCHEMBL11284668 | 0.89 | PDCD1 (0.64) | ALDH1A1KMT2AMEN1PKMDHODH | |
| SCHEMBL328588 | 0.89 | ALDH1A1 (0.82) | ALDH1A1KMT2AMEN1PKMNPSR1 | |
| SCHEMBL14087662 | 0.87 | DHODH (0.69) | ALDH1A1KMT2AMEN1PKMDHODH | |
| SCHEMBL4669122 | 0.86 | LMNA (0.76) | ALDH1A1KMT2AMEN1PKMDHODH | |
| SCHEMBL11405554 | 0.86 | LMNA (0.76) | ALDH1A1KMT2AMEN1PKMDHODH | |
| SCHEMBL15183709 | 0.86 | KMT2A (0.77) | KMT2AMEN1PKMDHODHPPARG | |
| SCHEMBL28965115 | 0.86 | LMNA (0.76) | ALDH1A1KMT2AMEN1PKMNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2115111-B1 | BENZOPHENONE OR BENZOIC ACID ANILIDE DERIVATIVES CONTAINING CARBOXYL GROUPS AS ENZYME STABILIZERS | HENKEL AG & CO KGAA (DE) | 2014-04-30 | — | — | EP | claimed |
| US-7968508-B2 | Benzophenone or benzoic acid anilide derivatives containing carboxyl groups as enzyme stabilizers | HENKEL AG & CO. KGAA (DE) | 2011-06-28 | — | — | US | claimed |
| US-20100062964-A1 | Benzophenone or Benzoic Acid Anilide Derivatives containing Carboxyl Groups as Enzyme Stabilizers | HENKEL AG & CO., KGAA (DE) | 2010-03-11 | — | — | US | claimed |
| EP-0172890-A4 | ACCUMULATED THERMAL EXPOSURE RESPONDER AND METHOD OF USE. | CONTROLLED CHEMICALS INC (US) | 1989-07-25 | — | — | EP | claimed |
| EP-0172890-A1 | ACCUMULATED THERMAL EXPOSURE RESPONDER AND METHOD OF USE | CONTROLLED CHEMICALS INCORPORATED (US) | 1986-03-05 | — | — | EP | claimed |
| WO-1985003775-A1 | ACCUMULATED THERMAL EXPOSURE RESPONDER AND METHOD OF USE | CONTROLLED CHEMICALS INCORPORATED (US) | 1985-08-29 | — | — | WO | claimed |
| US-4533640-A | INDICATING DETERIORATION OF PERISHABLE GOODS | CONTROLLED CHEMICALS INCORPORATED A MI CORP | 1985-08-06 | — | — | US | claimed |
| JP-55133425-A | — | — | None | — | — | JP | disclosed |
| US-11045476-B2 | Compounds and methods for inducing chondrogenesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2021-06-29 | — | — | US | disclosed |
| US-20200188407-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | THE SCRIPPS RESEARCH INSTITUTE | 2020-06-18 | — | — | US | disclosed |
| US-10166237-B2 | Compounds and methods for inducing chondrogenesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2019-01-01 | — | — | US | disclosed |
| US-20170112843-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | THE SCRIPPS RESEARCH INSTITUTE | 2017-04-27 | — | — | US | disclosed |
| US-9464065-B2 | Compounds and methods for inducing chondrogenesis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-10-11 | — | — | US | disclosed |
| WO-1994025501-A1 | EPOXY RESINS CONTAINING THIADIAZOLE AND/OR OXADIAZOLE MOIETIES | THE DOW CHEMICAL COMPANY (US) | 1994-11-10 | — | — | WO | disclosed |
| EP-0172890-A4 | ACCUMULATED THERMAL EXPOSURE RESPONDER AND METHOD OF USE. | CONTROLLED CHEMICALS INC (US) | 1989-07-25 | — | — | EP | disclosed |
| US-4795714-A | MONITOR OF THERMAL EXPOSURE WHICH SIGNALS DETERIORATION OF PERSHIBLE GOODS | SHAFER JULES A (US) | 1989-01-03 | — | — | US | disclosed |
| EP-0172890-A1 | ACCUMULATED THERMAL EXPOSURE RESPONDER AND METHOD OF USE | CONTROLLED CHEMICALS INCORPORATED (US) | 1986-03-05 | — | — | EP | disclosed |
| WO-1985003775-A1 | ACCUMULATED THERMAL EXPOSURE RESPONDER AND METHOD OF USE | CONTROLLED CHEMICALS INCORPORATED (US) | 1985-08-29 | — | — | WO | disclosed |
| US-4533640-A | INDICATING DETERIORATION OF PERISHABLE GOODS | CONTROLLED CHEMICALS INCORPORATED A MI CORP | 1985-08-06 | — | — | US | disclosed |
| JP-S55133425-A | PREPARATION OF AMIDE GROUP-CONTAINING POLYESTER COPOLYMER | TORAY IND INC | 1980-10-17 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10166237-B2 | Compounds and methods for inducing chondrogenesis | COL2A1, BMP4, BMP2 | ALDH1A1 63/4885KMT2A 3000/4885MEN1 4660/4885 |
| US-11045476-B2 | Compounds and methods for inducing chondrogenesis | COL2A1, BMP4, COL1A1 | ALDH1A1 52/4885KMT2A 3871/4885MEN1 4679/4885 |
| US-20170112843-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | COL2A1, BMP4, BMP2 | ALDH1A1 63/4885KMT2A 3000/4885MEN1 4660/4885 |
| US-20200188407-A1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | COL2A1, BMP4, COL1A1 | ALDH1A1 52/4885KMT2A 3871/4885MEN1 4679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.