Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | WNT3A | P56704 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290919 | 0.93 | ADRB2 (0.48) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11638350 | 0.92 | ADRB2 (0.47) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL11290476 | 0.88 | ALOX15 (0.41) | ALOX15ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL11284412 | 0.87 | ALOX15 (0.45) | ALOX15ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL11288057 | 0.83 | ADRB2 (0.46) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL11287399 | 0.81 | ADRB2 (0.48) | ALOX15ADRB2ADRB1ADRB3KMT2A | |
| SCHEMBL11287514 | 0.81 | MAPT (0.46) | KMT2ANPC1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11287537 | 0.81 | MAPT (0.46) | ADRB2ADRB1ADRB3KMT2AMEN1 | |
| SCHEMBL11288774 | 0.81 | ALOX15 (0.44) | ALOX15ADRB2ADRB1ADRB3PDE4A | |
| SCHEMBL11289627 | 0.80 | ALOX15 (0.43) | ALOX15KMT2AMEN1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |