Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | WNT3A | P56704 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11290912 | 0.90 | CTNNB1 (0.45) | ADRB2ADRB1ADRB3CTNNB1WNT3A | |
| Hydrochloric Acid SCHEMBL11638344 | 0.88 | CTNNB1 (0.44) | ADRB2ADRB1ADRB3CTNNB1WNT3A | |
| SCHEMBL11290478 | 0.88 | ALOX15 (0.47) | ALOX15ADRB2ADRB1ADRB3CTNNB1 | |
| SCHEMBL11284406 | 0.83 | ALOX15 (0.39) | ALOX15CTNNB1WNT3AALDH1A1KMT2A | |
| SCHEMBL11288054 | 0.82 | TTR (0.45) | ADRB2ADRB1ADRB3CTNNB1WNT3A | |
| SCHEMBL11288774 | 0.80 | ALOX15 (0.44) | ALOX15ADRB2ADRB1ADRB3PDE4A | |
| SCHEMBL11290919 | 0.80 | ADRB2 (0.48) | ADRB2ADRB1ADRB3CTNNB1WNT3A | |
| Hydrochloric Acid SCHEMBL11638350 | 0.79 | ADRB2 (0.47) | ADRB2ADRB1ADRB3CTNNB1WNT3A | |
| Hydrochloric Acid SCHEMBL11287403 | 0.78 | SLC22A3 (0.46) | ALOX15ADRB2ADRB1ADRB3ALDH1A1 | |
| SCHEMBL11289627 | 0.77 | ALOX15 (0.43) | ALOX15ALDH1A1KMT2ALMNAPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4336400-A | BRONCHODILATOR AGENTS, CARDIOVASCULAR STIMULANTS | STERLING DRUG INC. (US) | 1982-06-22 | — | — | US | disclosed |
| US-RE30241-E | BRONCHODILATION, ADRENERGIC STIMULANTS | STERLING DRUG INC. (US) | 1980-03-25 | — | — | US | disclosed |
| US-4138581-A | BRONCHODILATOR AGENTS, ADRENERGIC STIMULANTS | STERLING DRUGS INC. (US) | 1979-02-06 | — | — | US | disclosed |