Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 2/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10926001 | 0.86 | PDE3B (0.34) | PDE3BPDE3ATYMPDHODHL3MBTL1 | |
| SCHEMBL9786614 | 0.80 | PDE3B (0.49) | PDE3BPDE3ATYMPL3MBTL1 | |
| SCHEMBL9786577 | 0.70 | L3MBTL1 (0.46) | PDE3BPDE3AL3MBTL1 | |
| SCHEMBL10876610 | 0.67 | GSK3B (0.49) | PDE3BPDE3ADHODH | |
| SCHEMBL10968412 | 0.62 | JAK2 (0.45) | PDE3BPDE3ATYMPDHODHL3MBTL1 | |
| SCHEMBL10918334 | 0.62 | TYMP (0.50) | PDE3BPDE3ATYMPL3MBTL1 | |
| SCHEMBL10970603 | 0.61 | CREBBP (0.40) | PDE3BPDE3ATYMPDHODHL3MBTL1 | |
| SCHEMBL10968694 | 0.61 | PDE3B (0.33) | PDE3BPDE3ATYMPL3MBTL1 | |
| SCHEMBL20535215 | 0.58 | ALDH1A1 (0.50) | — | |
| SCHEMBL7065550 | 0.58 | L3MBTL1 (0.34) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064705-A1 | 5-Aminomethyl-2,3-dihydro-2-oxo-1H-imidazole-4-carboxylic acid derivatives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-11-17 | — | — | EP | disclosed |