Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 6/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29315212 | 0.98 | GRM4 (0.42) | GRM4CTSKMMP9ADAM17CTSL | |
| SCHEMBL29315213 | 0.83 | CA1 (0.47) | GRM4CTSKNAAAEPHX1CTSL | |
| SCHEMBL11397821 | 0.81 | CTSK (0.44) | CTSKEPHX1CTSLCTSB | |
| SCHEMBL7066347 | 0.81 | GRM4 (0.41) | GRM4CTSKMMP9ADAM17EPHX1 | |
| SCHEMBL29315215 | 0.80 | BCHE (0.39) | GRM4CTSKNAAAEPHX1 | |
| SCHEMBL24754202 | 0.79 | — | — | |
| SCHEMBL5909473 | 0.79 | GRM4 (0.56) | GRM4CTSKEPHX1ALDH1A1CTSB | |
| SCHEMBL20979462 | 0.77 | GRM4 (0.38) | GRM4CTSKMMP9ADAM17CTSL | |
| SCHEMBL10169316 | 0.77 | GRM4 (0.39) | GRM4CTSKEPHX1CTSLCTSB | |
| SCHEMBL30606190 | 0.77 | GRM4 (0.39) | GRM4CTSKMMP9ADAM17EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4318900-A | STIMULANTS | WILKINSON SWORD LIMITED (GB) | 1982-03-09 | — | — | US | disclosed |
| US-4248859-A | USED IN EDIBLE AND TOPICAL PREPARATIONS | WILKINSON SWORD LIMITED (GB) | 1981-02-03 | — | — | US | disclosed |