Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.45 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.44 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11294355 | 0.99 | PLA2G2A (0.47) | HTTNR5A2NR5A1PLA2G2APLA2G5 | |
| Hydrochloric Acid SCHEMBL11288203 | 0.97 | PLA2G2A (0.46) | HTTNR5A2NR5A1PLA2G2APLA2G5 | |
| SCHEMBL11288335 | 0.96 | NR5A2 (0.46) | HTTNR5A2NR5A1PLA2G2APLA2G5 | |
| SCHEMBL11289849 | 0.90 | ALDH1A1 (0.45) | HTTNR5A2NR5A1HSD17B3MEN1 | |
| SCHEMBL5335689 | 0.84 | NR5A2 (0.63) | HTTNR5A2NR5A1PLA2G2APLA2G5 | |
| SCHEMBL11293235 | 0.84 | CYP1A2 (0.40) | NR5A2NR5A1MEN1KMT2AALDH1A1 | |
| SCHEMBL11286999 | 0.83 | TSHR (0.41) | NR5A2NR5A1CA2MEN1KMT2A | |
| SCHEMBL10322111 | 0.83 | MEN1 (0.41) | NR5A2NR5A1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11295054 | 0.83 | CYP1A2 (0.39) | NR5A2NR5A1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11289618 | 0.82 | NR5A2 (0.40) | NR5A2NR5A1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |