Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NR5A2 | O00482 | 1/20 | 0.40 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11289618 | 0.98 | NR5A2 (0.40) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11289849 | 0.87 | ALDH1A1 (0.45) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11288335 | 0.84 | NR5A2 (0.46) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11291145 | 0.83 | HTT (0.46) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11294355 | 0.82 | PLA2G2A (0.47) | MEN1KMT2AMAPTALDH1A1NR5A2 | |
| SCHEMBL11291778 | 0.81 | NR5A2 (0.37) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL5344407 | 0.81 | NR5A2 (0.58) | KMT2AALDH1A1GAARECQLNR5A2 | |
| Hydrochloric Acid SCHEMBL11288203 | 0.81 | PLA2G2A (0.46) | MEN1KMT2AMAPTALDH1A1NR5A2 | |
| SCHEMBL11307428 | 0.81 | MIF (0.40) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL11289049 | 0.81 | MEN1 (0.44) | MEN1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | claimed |
| JP-57193428-A | — | — | None | — | — | JP | disclosed |
| WO-2014176460-A1 | METHODS OF TREATING BEHAVIORIAL AND/OR MENTAL DISORDERS | CHAU DAVID T (US) | 2014-10-30 | — | — | WO | disclosed |
| US-8486922-B2 | Composition | CHEN CHIEN-HUNG (TW) | 2013-07-16 | — | — | US | disclosed |
| US-20120183600-A1 | NOVEL COMPOSITION FOR TREATING METABOLIC SYNDROME AND OTHER CONDITIONS | CHEN CHIEN-HUNG (US) | 2012-07-19 | — | — | US | disclosed |
| EP-0065874-A1 | 2-Aminophenol derivatives, methods for their preparation and composition containing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 1982-12-01 | — | — | EP | disclosed |
| JP-S57193428-A | 2-ACYL-6-AMINOPHENOL DERIVATIVE, ITS PREPARATION, AND REMEDY FOR DISEASES CAUSED BY LEUCOTRIENE CONTAINING THE SAME | ONO PHARMACEUT CO LTD | 1982-11-27 | — | — | JP | disclosed |