Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11293832 | 0.88 | CA2 (0.58) | ATMKDM4EPOLBCYP1A2CYP3A4 | |
| SCHEMBL31157848 | 0.77 | CYP19A1 (0.77) | CYP19A1ATMKDM4ESTAT3POLB | |
| SCHEMBL16641094 | 0.77 | CYP19A1 (0.77) | CYP19A1ATMKDM4ESTAT3POLB | |
| SCHEMBL11292976 | 0.76 | ALOX15 (0.46) | KDM4ECYP1A2CYP2D6BLMPMP22 | |
| SCHEMBL10335393 | 0.75 | CYP19A1 (0.81) | CYP19A1ATMKDM4ESTAT3POLB | |
| SCHEMBL11291865 | 0.75 | CYP19A1 (0.51) | CYP19A1ATMKDM4EPOLBCYP1A2 | |
| SCHEMBL10738811 | 0.71 | CYP19A1 (0.50) | CYP19A1ATMKDM4EPOLBCYP1A2 | |
| SCHEMBL20106695 | 0.70 | POLB (0.78) | KDM4EPOLBTSHRSMN1; SMN2 | |
| SCHEMBL10905429 | 0.70 | LTA4H (0.47) | ATMKDM4ECYP2D6LMNASMN1; SMN2 | |
| SCHEMBL30869991 | 0.69 | ATM (0.70) | CYP19A1ATMKDM4ESTAT3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064820-A1 | Substituted imidazole and imidazoline derivatives and their preparation and use | Farmos-Yhtyma Oy (FI) | 1982-11-17 | — | — | EP | disclosed |