Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.47 |
| ▸ | GCGR | P47871 | 3/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.47 |
| ▸ | CDK2 | P24941 | 4/20 | 0.45 |
| ▸ | MARK3 | P27448 | 3/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.45 |
| ▸ | MARK2 | Q7KZI7 | 3/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.45 |
| ▸ | CSF1R | P07333 | 2/20 | 0.45 |
| ▸ | FER | P16591 | 2/20 | 0.45 |
| ▸ | FLT4 | P35916 | 2/20 | 0.45 |
| ▸ | FLT3 | P36888 | 2/20 | 0.45 |
| ▸ | CLK2 | P49760 | 2/20 | 0.45 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1128951 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MAPK1MAPK13GCGRMAPK12 | |
| SCHEMBL11719560 | 0.89 | ALDH1A1 (0.42) | ALDH1A1MAPK1MAPK13GCGRMAPK12 | |
| SCHEMBL218119 | 0.88 | ALOX15 (0.52) | ALDH1A1MAPTALOX15NPC1RAB9A | |
| SCHEMBL15022262 | 0.86 | MAPK14 (0.47) | MAPK1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL5443428 | 0.86 | MAPK14 (0.47) | MAPK1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL3108967 | 0.81 | TDP1 (0.52) | ALDH1A1MAPK1CDK2NR1H2NR1H3 | |
| SCHEMBL28329372 | 0.81 | ADORA1 (0.49) | ALDH1A1MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL28197453 | 0.80 | ALOX15 (0.43) | ALDH1A1AURKBMAP4K4CSF1RCLK4 | |
| SCHEMBL5256518 | 0.79 | NOTUM (0.52) | MAPK1MAPK13MAPK12MAPK11MAPK14 | |
| Pyridine SCHEMBL27988808 | 0.79 | ALOX15 (0.43) | ALDH1A1MAPK1MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2282742-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | Infinity Pharmaceuticals, Inc. (US) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009126691-A1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | INFINITY PHARMACEUTICALS, INC (US) | 2009-10-15 | — | — | WO | disclosed |