SCHEMBL3108967

SCHEMBL3108967

Cc1ccc(-c2c[nH]nc2-c2ccccc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.52
ALDH1A1 P00352 5/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
NR1H2 P55055 1/20 0.45
NR1H3 Q13133 1/20 0.45
MAPK1 P28482 1/20 0.45
NPC1 O15118 1/20 0.43
POLB P06746 1/20 0.43
HPGD P15428 1/20 0.43
NFKB1 P19838 1/20 0.43
RAB9A P51151 1/20 0.43
NFKB2 Q00653 1/20 0.43
RELA Q04206 1/20 0.43
ALOX15 P16050 1/20 0.42
ADORA2A P29274 3/20 0.41
ADORA1 P30542 3/20 0.41
CCNA2 P20248 1/20 0.41
CDK2 P24941 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL218119 0.88 ALOX15 (0.52) ALDH1A1SMN1; SMN2NPC1HPGDRAB9A
SCHEMBL4447414 0.86 ACHE (0.45) TDP1ALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL28329372 0.81 ADORA1 (0.49) ALDH1A1MEN1KMT2ASMN1; SMN2ALOX15
SCHEMBL1129154 0.81 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ASMN1; SMN2NR1H2
SCHEMBL1128951 0.81 ALDH1A1 (0.50) ALDH1A1MEN1KMT2ASMN1; SMN2NR1H2
SCHEMBL7780697 0.80 PTGS2 (0.54)
SCHEMBL28197453 0.80 ALOX15 (0.43) ALDH1A1POLBHPGDRAB9AALOX15
SCHEMBL5256518 0.79 NOTUM (0.52) SMN1; SMN2MAPK1NPC1RAB9AALOX15
Pyridine SCHEMBL27988808 0.79 ALOX15 (0.43) ALDH1A1SMN1; SMN2MAPK1HPGDALOX15
SCHEMBL7779925 0.79 PTGS2 (0.54) ADORA1ADORA3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2259360-B1 Organic light emitting devices having carrier transporting layers comprising metal complexes UNIV PRINCETON (US) 2021-11-03 EP disclosed
EP-1421828-B1 ORGANIC LIGHT EMITTING DEVICES HAVING CARRIER TRANSPORTING LAYERS COMPRISING METAL COMPLEXES UNIV PRINCETON (US) 2015-10-14 EP disclosed
CN-101694867-B Organic light emitting devices having carrier blocking layers comprising metal complexes TRUSTEES OF PRINCETON UNIVERSITY (US) 2014-10-22 CN disclosed
EP-2259360-A2 Organic light emitting devices having carrier transporting layers comprising metal complexes The Trustees of Princeton University (US) 2010-12-08 EP disclosed
CN-101694867-A Organic light emitting devices having carrier blocking layers comprising metal complexes UNIV PRINCETON 2010-04-14 CN disclosed
CN-100511760-C Organic light-emitting element having carrier transport layer containing metal complex UNIV PRINCETON UNIV SOUTHERN C (US) 2009-07-08 CN disclosed
EP-1421828-A4 ORGANIC LIGHT EMITTING DEVICES HAVING CARRIER TRANSPORTING LAYERS COMPRISING METAL COMPLEXES UNIV SOUTHERN CALIFORNIA (US) 2008-04-23 EP disclosed
US-7288331-B2 Organic light emitting devices having carrier transporting layers comprising metal complexes THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2007-10-30 US disclosed
US-20060257685-A1 Organometallic complex having multi-dentate ligands; improved efficiency and stability THOMPSON MARK E 2006-11-16 US disclosed
US-7078113-B2 Organic light emitting devices having carrier transporting layers comprising metal complexes THE UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2006-07-18 US disclosed
CN-1628491-A Organic light-emitting element having carrier transport layer containing metal complex UNIV PRINCETON (US) 2005-06-15 CN disclosed
EP-1421828-A1 ORGANIC LIGHT EMITTING DEVICES HAVING CARRIER TRANSPORTING LAYERS COMPRISING METAL COMPLEXES UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2004-05-26 EP disclosed
US-20030059647-A1 Organic light emitting devices having carrier transporting layers comprising metal complexes THE UNIVERSITY OF SOUTHERN CALIFORNIA 2003-03-27 US disclosed
WO-2003022008-A1 ORGANIC LIGHT EMITTING DEVICES HAVING CARRIER TRANSPORTING LAYERS COMPRISING METAL COMPLEXES THE TRUSTEES OF PRINCETON UNIVERSITY (US) 2003-03-13 WO disclosed